Literature DB >> 9816523

Intracoronary radiation using radioisotope solution-filled balloons.

J Weinberger1.   

Abstract

A substantial body of experimental evidence suggests that local application of radiation at sites of angioplasty or stent implantation prevents neointima formation. Recent initial clinical studies report a significant reduction in clinical restenosis rates when gamma emitting radiation sources are used to treat the site of coronary intervention. Because of the energy of therapeutic gamma sources and the shielding requirements, it would be far preferable to deliver ionizing radiation using a local beta emitter. This report discusses a number of the physical, biological, and technical parameters involved in radiation from a balloon angioplasty catheter filled with a beta emitting radioisotope solution.

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Year:  1998        PMID： 9816523     DOI： 10.1007/bf03043602

Source DB:  PubMed          Journal:  Herz        ISSN： 0340-9937            Impact factor:   1.443


  8 in total

1.  Endovascular beta-radiation to reduce restenosis after coronary balloon angioplasty: results of the beta energy restenosis trial (BERT).

Authors:  S B King; D O Williams; P Chougule; J L Klein; R Waksman; R Hilstead; J Macdonald; K Anderberg; I R Crocker
Journal:  Circulation       Date:  1998-05-26       Impact factor: 29.690

2.  Dosimetric considerations for catheter-based beta and gamma emitters in the therapy of neointimal hyperplasia in human coronary arteries.

Authors:  H I Amols; M Zaider; J Weinberger; R Ennis; P B Schiff; L E Reinstein
Journal:  Int J Radiat Oncol Biol Phys       Date:  1996-11-01       Impact factor: 7.038

3.  Catheter-based radiotherapy to inhibit restenosis after coronary stenting.

Authors:  P S Teirstein; V Massullo; S Jani; J J Popma; G S Mintz; R J Russo; R A Schatz; E M Guarneri; S Steuterman; N B Morris; M B Leon; P Tripuraneni
Journal:  N Engl J Med       Date:  1997-06-12       Impact factor: 91.245

4.  192IR endovascular brachytherapy for avoidance of intimal hyperplasia after percutaneous transluminal angioplasty and stent implantation in peripheral vessels: 6 years of experience.

Authors:  B Schopohl; D Leirmann; L J Pohlit; R Heyd; G Strassmann; R Bauersachs; D Schulte-Huermann; C G Rahl; K H Manegold; J Kollath; H D Bottcher
Journal:  Int J Radiat Oncol Biol Phys       Date:  1996-11-01       Impact factor: 7.038

5.  High dose rate intracoronary radiation for inhibition of neointimal formation in the stented and balloon-injured porcine models of restenosis: angiographic, morphometric, and histopathologic analyses.

Authors:  W Mazur; M N Ali; M M Khan; S F Dabaghi; C A DeFelice; P Paradis; E B Butler; A E Wright; L F Fajardo; B A French; A E Raizner
Journal:  Int J Radiat Oncol Biol Phys       Date:  1996-11-01       Impact factor: 7.038

6.  Intracoronary irradiation: dose response for the prevention of restenosis in swine.

Authors:  J Weinberger; H Amols; R D Ennis; A Schwartz; J G Wiedermann; C Marboe
Journal:  Int J Radiat Oncol Biol Phys       Date:  1996-11-01       Impact factor: 7.038

7.  Dosimetry of a radioactive coronary balloon dilatation catheter for treatment of neointimal hyperplasia.

Authors:  H I Amols; L E Reinstein; J Weinberger
Journal:  Med Phys       Date:  1996-10       Impact factor: 4.071

8.  Intracoronary irradiation markedly reduces neointimal proliferation after balloon angioplasty in swine: persistent benefit at 6-month follow-up.

Authors:  J G Wiedermann; C Marboe; H Amols; A Schwartz; J Weinberger
Journal:  J Am Coll Cardiol       Date:  1995-05       Impact factor: 24.094
  8 in total
  1 in total

1.  Monte Carlo dose simulation for intracoronary radiation therapy with a rhenium 188 solution-filled balloon with contrast medium.

Authors:  Eun-Hee Kim; Dae Hyuk Moon; Seung-Jun Oh; Chang-Woon Choi; Sang-Moo Lim; Myeong-Ki Hong; Seong-Wook Park
Journal:  J Nucl Cardiol       Date:  2002 May-Jun       Impact factor: 5.952
  1 in total

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