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Literature DB >> 9813774

Autism: the phenotype in relatives.

A Bailey¹, S Palferman, L Heavey, A Le Couteur.

Abstract

There is broad agreement that genetic influences are central in the development of idiopathic autism. Whether relatives manifest genetically related milder phenotypes, and if so how these relate to autism proper, has proved a more contentious issue. A review of the relevant studies indicates that relatives are sometimes affected by difficulties that appear conceptually related to autistic behaviors. These range in severity from pervasive developmental disorders to abnormalities in only one area of functioning, and possibly extend to related personality traits. Issues involved in clarifying the components of milder phenotypes and their relationship to autism are outlined.

Entities: Disease

Mesh：

Year: 1998 PMID： 9813774 DOI： 10.1023/a:1026048320785

Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257

79 in total

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Authors: J Piven; M Wzorek; R Landa; J Lainhart; P Bolton; G A Chase; S Folstein
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Review 10. Affective disorders in people with autism: a review of published cases.

Authors: J E Lainhart; S E Folstein
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123 in total

1. A genomic screen of autism: evidence for a multilocus etiology.

Authors: N Risch; D Spiker; L Lotspeich; N Nouri; D Hinds; J Hallmayer; L Kalaydjieva; P McCague; S Dimiceli; T Pitts; L Nguyen; J Yang; C Harper; D Thorpe; S Vermeer; H Young; J Hebert; A Lin; J Ferguson; C Chiotti; S Wiese-Slater; T Rogers; B Salmon; P Nicholas; P B Petersen; C Pingree; W McMahon; D L Wong; L L Cavalli-Sforza; H C Kraemer; R M Myers
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Journal: Hum Hered Date: 2004 Impact factor: 0.444

6. Contrast sensitivity for motion detection and direction discrimination in adolescents with autism spectrum disorders and their siblings.

Authors: Hwan Cui Koh; Elizabeth Milne; Karen Dobkins
Journal: Neuropsychologia Date: 2010-10-19 Impact factor: 3.139

7. Infants' pre-empathic behaviors are associated with language skills.

Authors: Ted Hutman; Agata Rozga; Angeline DeLaurentis; Marian Sigman; Mirella Dapretto
Journal: Infant Behav Dev Date: 2012-06-20

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Authors: Gwen L Schmidt; Lila K Kimel; Erin Winterrowd; Bruce F Pennington; Susan L Hepburn; Donald C Rojas
Journal: J Clin Exp Neuropsychol Date: 2008-07 Impact factor: 2.475