Literature DB >> 9795033

Antimycobacterial activity of lichen metabolites in vitro.

K Ingólfsdóttir1, G A Chung, V G Skúlason, S R Gissurarson, M Vilhelmsdóttir.   

Abstract

Several compounds, whose structures represent the most common chemical classes of lichen metabolites, were screened for in vitro activity against Mycobacterium aurum, a non-pathogenic organism with a similar sensitivity profile to M. tuberculosis. Of the compounds tested, usnic acid from Cladonia arbuscula exhibited the highest activity with an MIC value of 32 microg/ml. Atranorin and lobaric acid, both isolated from Stereocaulon alpinum, salazinic acid from Parmelia saxatilis and protolichesterinic acid from Cetraria islandica all showed MIC values >/=125 microg/ml.

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Year:  1998        PMID： 9795033     DOI： 10.1016/s0928-0987(97)00078-x

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN： 0928-0987            Impact factor:   4.384


  12 in total

1.  Beta-orcinol metabolites from the lichen Hypotrachyna revoluta.

Authors:  Panagiota Papadopoulou; Olga Tzakou; Constantinos Vagias; Panagiotis Kefalas; Vassilios Roussis
Journal:  Molecules       Date:  2007-05-12       Impact factor: 4.411

Review 2.  Review of usnic acid and Usnea barbata toxicity.

Authors:  Lei Guo; Qiang Shi; Jia-Long Fang; Nan Mei; A Afshan Ali; Sherry M Lewis; Julian E A Leakey; Vasilios H Frankos
Journal:  J Environ Sci Health C Environ Carcinog Ecotoxicol Rev       Date:  2008 Oct-Dec       Impact factor: 3.781

3.  Ozone reactivity and free radical scavenging behavior of phenolic secondary metabolites in lichens exposed to chronic oxidant air pollution from Mexico City.

Authors:  N Valencia-Islas; A Zambrano; J L Rojas
Journal:  J Chem Ecol       Date:  2007-07-10       Impact factor: 2.626

4.  Usnic Acid Treatment Changes the Composition of Mycobacterium tuberculosis Cell Envelope and Alters Bacterial Redox Status.

Authors:  Elwira Sieniawska; Rafal Sawicki; Wieslaw Truszkiewicz; Andrey S Marchev; Milen I Georgiev
Journal:  mSystems       Date:  2021-05-04       Impact factor: 6.496

5.  Potent activity of the lichen antibiotic (+)-usnic acid against clinical isolates of vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus.

Authors:  Hannu Elo; Jorma Matikainen; Eila Pelttari
Journal:  Naturwissenschaften       Date:  2007-01-24

6.  Collagen-based films containing liposome-loaded usnic acid as dressing for dermal burn healing.

Authors:  Paula S Nunes; Ricardo L C Albuquerque; Danielle R R Cavalcante; Marx D M Dantas; Juliana C Cardoso; Marília S Bezerra; Jamille C C Souza; Mairim Russo Serafini; Lucindo J Quitans; Leonardo R Bonjardim; Adriano A S Araújo
Journal:  J Biomed Biotechnol       Date:  2011-01-11

7.  Determination of Teloschistes flavicans (sw) norm anti-inflammatory activity.

Authors:  Eugênia C Pereira; Nicácio H da Silva; Renata Almeida Santos; Ana Patrícia Paiva Sudário; Antonio Alfredo Rodrigues E Silva; Maria Bernadete de Sousa Maia
Journal:  Pharmacognosy Res       Date:  2010-07

8.  In Vitro Antimicrobial Potential of the Lichen Parmotrema sp. Extracts against Various Pathogens.

Authors:  Ritika Chauhan; Jayanthi Abraham
Journal:  Iran J Basic Med Sci       Date:  2013-07       Impact factor: 2.699

9.  Effects of the encapsulation of usnic acid into liposomes and interactions with antituberculous agents against multidrug-resistant tuberculosis clinical isolates.

Authors:  Rafaela S Ferraz-Carvalho; Marcela A Pereira; Leonardo A Linhares; Mariane Cb Lira-Nogueira; Isabella Mf Cavalcanti; Nereide S Santos-Magalhães; Lílian Ml Montenegro
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-04-29       Impact factor: 2.743

10.  A Novel Derivative of (-)mycousnine Produced by the Endophytic Fungus Mycosphaerella nawae, Exhibits High and Selective Immunosuppressive Activity on T Cells.

Authors:  Li-Wei Wang; Jin-Liang Wang; Jing Chen; Jia-Jie Chen; Jia-Wei Shen; Xiao-Xiao Feng; Christian P Kubicek; Fu-Cheng Lin; Chu-Long Zhang; Feng-Yang Chen
Journal:  Front Microbiol       Date:  2017-07-05       Impact factor: 5.640
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