Literature DB >> 9790008

Lidocaine toxicity.

P Mehra1, A Caiazzo, P Maloney.   

Abstract

Local anesthetics are the most commonly used drugs in dentistry. The number of adverse reactions reported, particularly toxic reactions, are extraordinarily negligible. This article reports a case of lidocaine toxicity with its typical manifestation in a 37-yr-old healthy male. The toxic reaction followed transoral/transpharyngeal topical spraying of lidocaine preoperatively during preparation for general anesthesia. A review of dosages of the most commonly used local anesthetic drugs in dentistry and the management of a toxic reaction is presented. Clinicians need to be in a position to recognize and successfully manage this potential adverse reaction.

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Year:  1998        PMID: 9790008      PMCID: PMC2148953     

Source DB:  PubMed          Journal:  Anesth Prog        ISSN: 0003-3006


  3 in total

1.  Apneic and hypotensive effects of local anesthetic drugs in dogs and mice under general anesthesia.

Authors:  L A WOODS; J HAGGART
Journal:  Anesthesiology       Date:  1957 Nov-Dec       Impact factor: 7.892

Review 2.  Local anesthetics.

Authors:  J A Yagiela
Journal:  Anesth Prog       Date:  1991 Jul-Oct

3.  Reverse carotid blood flow--a possible explanation for some reactions to local anesthetics.

Authors:  J A Aldrete; R Narang; T Sada; S Tan Liem; G P Miller
Journal:  J Am Dent Assoc       Date:  1977-06       Impact factor: 3.634

  3 in total
  13 in total

1.  Central nervous system toxicity following topical skin application of lidocaine.

Authors:  Tal Brosh-Nissimov; Merav Ingbir; Iris Weintal; Mordechai Fried; Reuven Porat
Journal:  Eur J Clin Pharmacol       Date:  2004-10-02       Impact factor: 2.953

2.  Anesthesia methods in laser resurfacing.

Authors:  Sergio Gaitan; Ramsey Markus
Journal:  Semin Plast Surg       Date:  2012-08       Impact factor: 2.314

3.  Treatment of local anesthetic toxicity.

Authors:  R F Gerlach; J E Tanus-Santos
Journal:  Anesth Prog       Date:  1999

4.  A nomogram to calculate the maximum dose of local anaesthetic in a paediatric dental setting.

Authors:  J D Walker; A Summers; D J Williams
Journal:  Br Dent J       Date:  2015-04-24       Impact factor: 1.626

5.  A drug-laden elastomer for surgical treatment of anal fistula.

Authors:  Hairui Li; Bin Jiang; Jun Yan; Zhonghua Yang; Yanni Chen; Weiping Zhang; Alex C Choy; Chi-Ying M Lee; Lifeng Kang
Journal:  Drug Deliv Transl Res       Date:  2011-12       Impact factor: 4.617

6.  Development of lidocaine-coated microneedle product for rapid, safe, and prolonged local analgesic action.

Authors:  Ying Zhang; Ken Brown; Kris Siebenaler; Amy Determan; Daniel Dohmeier; Kris Hansen
Journal:  Pharm Res       Date:  2011-07-07       Impact factor: 4.200

7.  Population pharmacokinetics of lidocaine administered during and after cardiac surgery.

Authors:  Yung-Wei Hsu; Jacques Somma; Mark F Newman; Joseph P Mathew
Journal:  J Cardiothorac Vasc Anesth       Date:  2011-05-25       Impact factor: 2.628

8.  Differences in aerosol flow rates between disposable and reusable atomizers used for airway topicalization: implications for local anesthetic toxicity.

Authors:  Haotian Wang; R Zachary Ford; Andrew D Milne
Journal:  Can J Anaesth       Date:  2020-11-18       Impact factor: 5.063

9.  Even 'safe' medications need to be administered with care.

Authors:  Nancy Lutwak; Mary Ann Howland; Rosemarie Gambetta; Curt Dill
Journal:  BMJ Case Rep       Date:  2013-01-02

10.  A survey on the use of intravenous lidocaine infusion for acute pain in Scottish Hospitals.

Authors:  Eoghan D Meaney; Louise Reid; Devjit Srivastava
Journal:  Br J Pain       Date:  2019-08-29
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