Literature DB >> 9788953

Location of fluorotryptophan sequestered in an amphiphilic nanoparticle by rotational-echo double-resonance NMR.

A H Baugher1, J M Goetz, L M McDowell, H Huang, K L Wooley, J Schaefer.   

Abstract

Rotational-echo double-resonance (REDOR) 13C NMR spectra (with 19F dephasing) have been obtained of 6-fluorotryptophan complexed by a polymeric amphiphilic nanosphere consisting of a polystyrene core covalently attached to a poly(acrylic acid)-polyacrylamide shell. The REDOR spectra show that aromatic carbons from the polystyrene core and oxygenated carbons in the poly(acrylic acid)-polyacrylamide shell are both proximate to the 19F of 6-fluorotryptophan. Molecular modeling restrained by distances inferred from the REDOR spectra suggests that all of the 6-fluorotryptophans are in the shell but within 10 A of the core-shell interface.

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Year:  1998        PMID： 9788953      PMCID： PMC1299932          DOI： 10.1016/S0006-3495(98)77702-1

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  4 in total

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Authors:  J M Goetz; J Schaefer
Journal:  J Magn Reson       Date:  1997-08       Impact factor: 2.229

Review 2.  Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy.

Authors:  J P Behr
Journal:  Bioconjug Chem       Date:  1994 Sep-Oct       Impact factor: 4.774

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Authors:  J F Kukowska-Latallo; A U Bielinska; J Johnson; R Spindler; D A Tomalia; J R Baker
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4.  Parameters influencing the introduction of plasmid DNA into cells by the use of synthetic amphiphiles as a carrier system.

Authors:  I van der Woude; H W Visser; M B ter Beest; A Wagenaar; M H Ruiters; J B Engberts; D Hoekstra
Journal:  Biochim Biophys Acta       Date:  1995-11-22
  4 in total
  3 in total

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Journal:  J Magn Reson       Date:  2010-08-13       Impact factor: 2.229

2.  Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin.

Authors:  Lily Yun Lin; Nam S Lee; Jiahua Zhu; Andreas M Nyström; Darrin J Pochan; Richard B Dorshow; Karen L Wooley
Journal:  J Control Release       Date:  2011-01-15       Impact factor: 9.776

3.  Synthesis of crosslinkable diblock terpolymers PDPA-b-P(NMS-co-OEG) and preparation of shell-crosslinked pH/redox-dual responsive micelles as smart nanomaterials.

Authors:  Jingjing Sun; Zhao Wang; Amin Cao; Ruilong Sheng
Journal:  RSC Adv       Date:  2019-10-29       Impact factor: 4.036
  3 in total

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