Literature DB >> 9787638

Structure-specific DNA cleavage by 5' nucleases.

T A Ceska1, J R Sayers.   

Abstract

Many processes, such as DNA replication, recombination and repair, produce branched DNA structures. These bifurcated molecules are trimmed by a group of homologous 5'-3' exonucleases (also known as 5' nucleases) in structure-specific cleavage reactions. X-ray crystallographical and biochemical studies suggest that ssDNA substrates become threaded through the 5'-3' exonucleases, where hydrolysis is effected with the aid of divalent metal cations.

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Year:  1998        PMID： 9787638     DOI： 10.1016/s0968-0004(98)01259-6

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  21 in total

1.  Comparison of the 5' nuclease activities of taq DNA polymerase and its isolated nuclease domain.

Authors:  V Lyamichev; M A Brow; V E Varvel; J E Dahlberg
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-25       Impact factor: 11.205

2.  mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.

Authors:  David N Everly; Pinghui Feng; I Saira Mian; G Sullivan Read
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

3.  A real-time DNase assay (ReDA) based on PicoGreen fluorescence.

Authors:  Gökhan Tolun; Richard S Myers
Journal:  Nucleic Acids Res       Date:  2003-09-15       Impact factor: 16.971

4.  The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation.

Authors:  Franziska Bleichert; Sander Granneman; Yvonne N Osheim; Ann L Beyer; Susan J Baserga
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-12       Impact factor: 11.205

5.  The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs.

Authors:  Minfeng Shu; Brunella Taddeo; Bernard Roizman
Journal:  J Virol       Date:  2013-10-09       Impact factor: 5.103

6.  Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage.

Authors:  S J Garforth; T A Ceska; D Suck; J R Sayers
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-05       Impact factor: 11.205

7.  Molecular interactions of human Exo1 with DNA.

Authors:  Byung-in Lee Bi; Lam H Nguyen; Daniel Barsky; Mike Fernandes; David M Wilson
Journal:  Nucleic Acids Res       Date:  2002-02-15       Impact factor: 16.971

8.  Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease.

Authors:  J Qiu; Y Qian; P Frank; U Wintersberger; B Shen
Journal:  Mol Cell Biol       Date:  1999-12       Impact factor: 4.272

9.  A sequence-dependent exonuclease activity from Tetrahymena thermophila.

Authors:  Hui-I Kao Tom; Carol W Greider
Journal:  BMC Biochem       Date:  2010-11-16       Impact factor: 4.059

10.  Active site substitutions delineate distinct classes of eubacterial flap endonuclease.

Authors:  Lee M Allen; Michael R G Hodskinson; Jon R Sayers
Journal:  Biochem J       Date:  2009-03-01       Impact factor: 3.857
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