Literature DB >> 978175

The role of extracellular material in chick neurulation. I. Effects of concanavalin A.

H Lee, J B Sheffield, R G Nagele, G W Kalmus.   

Abstract

The distribution of extracellular material (ECM) in developing neuroepithelium of stage 8+ chick embryos was investigated using lanthanum nitrate. The temporal changes in the distribution of ECM was correlated with the ongoing morphogenetic movements. The most striking finding was that as the folds were about to meet, thick dense ECM appeared between leading edges. Concanavalin A inhibited neural tube closure by binding to cell surfaces and disrupting the usual distribution of ECM in developing neuroepithelium.

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Year:  1976        PMID： 978175     DOI： 10.1002/jez.1401980216

Source DB:  PubMed          Journal:  J Exp Zool        ISSN： 0022-104X


  5 in total

1.  Electron microscope study of the binding of Con A-gold to superficial and inner ectoderm layers ofXenopus laevis and its relation to the neural-inducing activity of this lectin.

Authors:  Lothar Tacke; Horst Grunz
Journal:  Rouxs Arch Dev Biol       Date:  1986-04

2.  The distribution of cell surface glycoconjugates during mouse secondary neurulation.

Authors:  C M Griffith; M J Wiley
Journal:  Anat Embryol (Berl)       Date:  1989

3.  The masking effect of sialic acid on Con A, PNA and SBA ectoderm binding sites during neurulation in the bantam chick embryo.

Authors:  H Takahashi
Journal:  Anat Embryol (Berl)       Date:  1992

4.  Phospholipase C-induced neural tube defects in the mouse embryo.

Authors:  K S O'Shea; M H Kaufman
Journal:  Experientia       Date:  1980-10-15

5.  Enzyme replacement therapy in Gaucher's disease: large-scale purification of glucocerebrosidase suitable for human administration.

Authors:  F S Furbish; H E Blair; J Shiloach; P G Pentchev; R O Brady
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205
  5 in total

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