Literature DB >> 7418810

Phospholipase C-induced neural tube defects in the mouse embryo.

K S O'Shea, M H Kaufman.   

Abstract

Mouse embryo neurulae were exposed in vitro to phospholipase C to examine the role of carbohydrate-rich extracellular material (ECM) during neurulation. Exposure of embryos to this agent for 12 h resulted in failure of closure of the neural tube. Ultrastructural examination revealed an absence of ECM from regions of the neural tube which failed to close.

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Year:  1980        PMID： 7418810     DOI： 10.1007/bf01976138

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  17 in total

1.  Surface coat of the palatal shelf epithelium during palatogenesis in mouse embryos.

Authors:  R Souchon
Journal:  Anat Embryol (Berl)       Date:  1975-08-09

2.  The role of extracellular material in chick neurulation. I. Effects of concanavalin A.

Authors:  H Lee; J B Sheffield; R G Nagele; G W Kalmus
Journal:  J Exp Zool       Date:  1976-11

3.  Fusion of nasal swellings in the mouse embryo: surface coat and initial contact.

Authors:  J D Gaare; J Langman
Journal:  Am J Anat       Date:  1977-11

4.  Surface coat on the epithelium of developing palatine shelves in the mouse as revealed by electron microscopy.

Authors:  R M Greene; D M Kochhar
Journal:  J Embryol Exp Morphol       Date:  1974-06

5.  Plaque acid production in hamsters pretreated with fluoride.

Authors:  D B Fitzgerald; R J Fitzgerald
Journal:  J Dent Res       Date:  1973 Jan-Feb       Impact factor: 6.116

6.  Culture of explanted rat embryos in rotating tubes.

Authors:  D A New; P T Coppola; S Terry
Journal:  J Reprod Fertil       Date:  1973-10

7.  A low-viscosity epoxy resin embedding medium for electron microscopy.

Authors:  A R Spurr
Journal:  J Ultrastruct Res       Date:  1969-01

8.  The fluid mosaic model of the structure of cell membranes.

Authors:  S J Singer; G L Nicolson
Journal:  Science       Date:  1972-02-18       Impact factor: 47.728

9.  A scanning electron microscopic and x-ray microanalytic study of cell surface material during amphibian neurulation.

Authors:  R W Rice; D J Moran
Journal:  J Exp Zool       Date:  1977-09

10.  Lanthanum staining of the surface coat of cells. Its enhancement by the use of fixatives containing Alcian blue or cetylpyridinium chloride.

Authors:  S M Shea
Journal:  J Cell Biol       Date:  1971-12       Impact factor: 10.539
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  6 in total

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2.  5-Azacytidine-induced exencephaly in mice.

Authors:  I K Takeuchi; Y K Takeuchi
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Journal:  Birth Defects Res       Date:  2017-01-30       Impact factor: 2.344

4.  Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival.

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Journal:  Neurol Med Chir (Tokyo)       Date:  2015-09-04       Impact factor: 1.742

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  6 in total

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