Literature DB >> 9771256

Melatonin treatment in an institutionalised child with psychomotor retardation and an irregular sleep-wake pattern.

G Pillar1, A Etzioni, E Shahar, P Lavie.   

Abstract

An institutionalised 13 year old girl with psychomotor retardation suffered from an irregular sleep-wake pattern. Multiple measurements of urinary sulphatoxy-melatonin (aMT6) concentrations were abnormally low, without any significant day-night differences. Administration of exogenous melatonin (3 mg) at 18:00 resulted in increased nocturnal urinary aMT6 concentrations and improvements in her sleep-wake pattern. Melatonin may help disabled children suffering from sleep disorders.

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Year:  1998        PMID： 9771256      PMCID： PMC1717628          DOI： 10.1136/adc.79.1.63

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  13 in total

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9.  Melatonin secretion in humans assessed by measuring its metabolite, 6-sulfatoxymelatonin.

Authors:  C J Bojkowski; J Arendt; M C Shih; S P Markey
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Authors:  J E Jan; H Espezel; R E Appleton
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