Literature DB >> 9766461

Spirofungin, a new antifungal antibiotic from Streptomyces violaceusniger Tü 4113.

A Höltzel1, C Kempter, J W Metzger, G Jung, I Groth, T Fritz, H P Fiedler.   

Abstract

A new secondary metabolite was detected in the culture filtrate and extracts of Streptomyces violaceusniger Tü 4113 by HPLC-diode-array and HPLC-electrospray-mass-spectrometry screening. The compound named spirofungin has a polyketide-spiroketal structure and shows various antifungal activities, particularly against yeasts.

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Year:  1998        PMID： 9766461     DOI： 10.7164/antibiotics.51.699

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

Review 1.  Search and discovery strategies for biotechnology: the paradigm shift.

Authors:  A T Bull; A C Ward; M Goodfellow
Journal:  Microbiol Mol Biol Rev       Date:  2000-09       Impact factor: 11.056

2.  Polyketide assembly by alkene-alkyne reductive cross-coupling: spiroketals through the union of homoallylic alcohols.

Authors:  Daniel P Canterbury; Glenn C Micalizio
Journal:  J Am Chem Soc       Date:  2010-06-09       Impact factor: 15.419

3.  Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

Authors:  Shunji Takahashi; Shingo Nagano; Toshihiko Nogawa; Naoki Kanoh; Masakazu Uramoto; Makoto Kawatani; Takeshi Shimizu; Takeshi Miyazawa; Yoshitsugu Shiro; Hiroyuki Osada
Journal:  J Biol Chem       Date:  2014-09-25       Impact factor: 5.157

4.  Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation.

Authors:  Shunji Takahashi; Atsushi Toyoda; Yasuyo Sekiyama; Hiroshi Takagi; Toshihiko Nogawa; Masakazu Uramoto; Ryuichiro Suzuki; Hiroyuki Koshino; Takuto Kumano; Suresh Panthee; Tohru Dairi; Jun Ishikawa; Haruo Ikeda; Yoshiyuki Sakaki; Hiroyuki Osada
Journal:  Nat Chem Biol       Date:  2011-06-05       Impact factor: 15.040

5.  Enantioselective total synthesis of spirofungins A and B.

Authors:  Michael T Crimmins; Elizabeth A O'Bryan
Journal:  Org Lett       Date:  2010-10-01       Impact factor: 6.005

6.  Metagenomic Analysis from the Interior of a Speleothem in Tjuv-Ante's Cave, Northern Sweden.

Authors:  Marie Lisandra Zepeda Mendoza; Johannes Lundberg; Magnus Ivarsson; Paula Campos; Johan A A Nylander; Therese Sallstedt; Love Dalen
Journal:  PLoS One       Date:  2016-03-17       Impact factor: 3.240

Review 7.  Asymmetric synthesis of naturally occurring spiroketals.

Authors:  B Rama Raju; Anil K Saikia
Journal:  Molecules       Date:  2008-08-28       Impact factor: 4.411

8.  Nigericin and Geldanamycin Are Phytotoxic Specialized Metabolites Produced by the Plant Pathogen Streptomyces sp. 11-1-2.

Authors:  Gustavo A Díaz-Cruz; Jingyu Liu; Kapil Tahlan; Dawn R D Bignell
Journal:  Microbiol Spectr       Date:  2022-02-28
  8 in total

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