| Literature DB >> 9765482 |
Abstract
The yeast two-hybrid system and in vitro binding assays were used to characterize 54 potential interactions between the proteins of Tf1, an LTR-retrotransposon found in Schizosaccharomyces pombe. The Tf1 integrase (IN) protein was found to interact strongly with itself and not with other control proteins. In addition, the IN core domain interacted strongly with itself and full-length IN. Interestingly, the two-hybrid analysis detected an interaction between the RNase H domain of reverse transcriptase and IN. The biological implications of these interactions are discussed.Entities:
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Year: 1998 PMID： 9765482 PMCID： PMC110354
Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103