Literature DB >> 9764699

Epidemiology of immediate and early trauma deaths at an urban Level I trauma center.

R Peng1, C Chang, D Gilmore, F Bongard.   

Abstract

The objective of this study is to identify and differentiate the injury patterns and causes of death among patients who died within the 1st hour and those in the period between 1 and 48 hours after hospital admission. Information was collected from the 1994 to 1996 trauma data base at an urban Level I trauma center. The records of 155 trauma patients who died within the 1st hour (immediate trauma death, ITD) and between 1 and 48 hours (early trauma death, ETD) were examined retrospectively. Total and constituent Injury Severity Score (ISS), Trauma Score (TS), and Glasgow Coma Score were analyzed. ITDs constituted 49 per cent of all deaths within 48 hours. Blunt mechanisms accounted for 37 per cent of ITDs and 40 per cent of ETDs (not significant), whereas penetrating trauma accounted for 59 per cent of ITDs and 56 per cent of ETDs (not significant). Exsanguination most commonly caused death among ITDs (54%) and head injury (51%) among ETDs (P < 0.01). Patients who died within the 1st hour had higher ISS (42.6 +/- 23.2, P < 0.03), lower TS (1.7 +/- 1.9, P < 0.0001), and lower Glasgow Coma Score (3.1 +/- 1.1, P < 0.0001) than those who died after the 1st hour. Patients with ITD had a significantly worse chest ISS than those with ETD (47.4 +/- 28.6 vs 19.0 +/- 19.1, P < 0.0001). We conclude that 1) ITD is caused primarily by exsanguination, whereas ETD is largely due to the sequelae of severe neurologic injury; 2) ITD has a significantly lower TS and higher ISS than ETD; and 3) thoracic injuries are more severe among patients with ITDs than among those with ETDs. The severity of thoracic injury among ITDs suggests that rapid surgical intervention is critical during the resuscitation of these severely injured patients.

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Year:  1998        PMID: 9764699

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  15 in total

1.  Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study.

Authors:  Mohammad H Rahbar; Erin E Fox; Deborah J del Junco; Bryan A Cotton; Jeanette M Podbielski; Nena Matijevic; Mitchell J Cohen; Martin A Schreiber; Jiajie Zhang; Parsa Mirhaji; Sarah J Duran; Robert J Reynolds; Ruby Benjamin-Garner; John B Holcomb
Journal:  Resuscitation       Date:  2011-10-12       Impact factor: 5.262

2.  Fixed rate of blood component improves the survival rate of patients in massive transfusion.

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Journal:  Biomed Rep       Date:  2012-10-29

3.  Predictive Models and Algorithms for the Need of Transfusion Including Massive Transfusion in Severely Injured Patients.

Authors:  Marc Maegele; Thomas Brockamp; Ulrike Nienaber; Christian Probst; Herbert Schoechl; Klaus Görlinger; Philip Spinella
Journal:  Transfus Med Hemother       Date:  2012-03-08       Impact factor: 3.747

4.  Warm fresh whole blood is independently associated with improved survival for patients with combat-related traumatic injuries.

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Review 5.  Resuscitation and transfusion principles for traumatic hemorrhagic shock.

Authors:  Philip C Spinella; John B Holcomb
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6.  Epidemiology and contemporary patterns of trauma deaths: changing place, similar pace, older face.

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7.  Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling.

Authors:  Luyun Zou; Shaolong Yang; Voraratt Champattanachai; Shunhua Hu; Irshad H Chaudry; Richard B Marchase; John C Chatham
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-12-19       Impact factor: 4.733

Review 8.  Optimal use of blood in trauma patients.

Authors:  John B Holcomb; Philip C Spinella
Journal:  Biologicals       Date:  2010-01-13       Impact factor: 1.856

9.  Cause of death and time of death distribution of trauma patients in a Level I trauma centre in the Netherlands.

Authors:  K W W Lansink; A C Gunning; L P H Leenen
Journal:  Eur J Trauma Emerg Surg       Date:  2013-05-07       Impact factor: 3.693

10.  Mortality Distribution in a Trauma System: From Data to Health Policy Recommendations.

Authors:  Ernestina Gomes; Rui Araújo; António Carneiro; Cláudia Dias; Fiona E Lecky; Altamiro Costa-Pereira
Journal:  Eur J Trauma Emerg Surg       Date:  2008-02-09       Impact factor: 3.693

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