Literature DB >> 24648928

Fixed rate of blood component improves the survival rate of patients in massive transfusion.

Wen-Ting Wang1, Yong-Hua Zhan2, Xing-Bin Hu1, Shi-Jie Mu1, Qun-Xing An1, Zhi-Xin Liu1, Xian-Qing Zhang1.   

Abstract

The aim of this study was to examine the manner in which varying proportions of serum and red blood cells (RBC) in massive blood transfusion affect the survival rates of patients with severe blood loss. Massive transfusion (MT) was determined as receiving ≥10 units of red blood cells in 24 h. The electronic medical records and blood transfusion information for the period January, 2002 to December, 2011 of patients with MT were examined. Moreover, we calculated the ratio of blood components and examined their correlation with survival. In total, 1,658 patients underwent MT during the period 2002-2011, with an overall of 28,030 units RBC, accounting for 2.8% of the total blood transfusion. In conclusion, fixing blood-component ratios has the potential to help improve survival rate in MT.

Entities:  

Keywords:  blood loss in trauma; infusion proportion; massive transfusion

Year:  2012        PMID: 24648928      PMCID: PMC3956216          DOI: 10.3892/br.2012.36

Source DB:  PubMed          Journal:  Biomed Rep        ISSN: 2049-9434


  31 in total

1.  Damage control resuscitation: the need for specific blood products to treat the coagulopathy of trauma.

Authors:  John R Hess; John B Holcomb; David B Hoyt
Journal:  Transfusion       Date:  2006-05       Impact factor: 3.157

Review 2.  Damage control resuscitation.

Authors:  John B Holcomb
Journal:  J Trauma       Date:  2007-06

3.  High plasma to red blood cell ratios are associated with lower mortality rates in patients receiving multiple transfusion (4≤red blood cell units<10) during acute trauma resuscitation.

Authors:  Arasch Wafaisade; Marc Maegele; Rolf Lefering; Maximilian Braun; Sigune Peiniger; Edmund Neugebauer; Bertil Bouillon
Journal:  J Trauma       Date:  2011-01

Review 4.  Transfusion management of trauma patients.

Authors:  Beth H Shaz; Christopher J Dente; Robert S Harris; Jana B MacLeod; Christopher D Hillyer
Journal:  Anesth Analg       Date:  2009-06       Impact factor: 5.108

Review 5.  The role of blood transfusion in the management of upper and lower intestinal tract bleeding.

Authors:  Sarah Hearnshaw; Simon Travis; Mike Murphy
Journal:  Best Pract Res Clin Gastroenterol       Date:  2008       Impact factor: 3.043

6.  Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival.

Authors:  Oliver L Gunter; Brigham K Au; James M Isbell; Nathan T Mowery; Pampee P Young; Bryan A Cotton
Journal:  J Trauma       Date:  2008-09

7.  The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.

Authors:  Matthew A Borgman; Philip C Spinella; Jeremy G Perkins; Kurt W Grathwohl; Thomas Repine; Alec C Beekley; James Sebesta; Donald Jenkins; Charles E Wade; John B Holcomb
Journal:  J Trauma       Date:  2007-10

Review 8.  The blood bank: from provider to partner in treatment of massively bleeding patients.

Authors:  Pär I Johansson
Journal:  Transfusion       Date:  2007-08       Impact factor: 3.157

9.  Minimizing dilutional coagulopathy in exsanguinating hemorrhage: a computer simulation.

Authors:  Asher Hirshberg; Mark Dugas; Eugenio I Banez; Bradford G Scott; Matthew J Wall; Kenneth L Mattox
Journal:  J Trauma       Date:  2003-03

10.  Epidemiology of trauma deaths: a reassessment.

Authors:  A Sauaia; F A Moore; E E Moore; K S Moser; R Brennan; R A Read; P T Pons
Journal:  J Trauma       Date:  1995-02
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