Literature DB >> 976433

[Effect of 6beta-Methoxy-9beta,10alpha-pregna-4,6-diene-3,20-dione (Ro 6-1963) on the steroid reductases in rat liver].

V Graef, S W Golf.   

Abstract

6beta-Methoxy-9beta,10 alpha-pregna-4,6-diene-3,20-dione inhibits the delta4-3-oxosteroid-5alpha-reduction in microsomes and the delta4-3-oxosteroid-5beta-reduction in the soluble fraction of male rat liver. The 3alpha- and 3beta-hydroxysteroid dehydrogenase are not inhibited by these substances.

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Year:  1976        PMID： 976433     DOI： 10.1007/BF01953075

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  2 in total

1.  Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedure.

Authors:  W L Gardiner; E C Herning
Journal:  Biochim Biophys Acta       Date:  1966-02-28

2.  [Studies on the mechanism of the delta-4-3-oxosteroid-5alpha-reduction in rat liver microsomes (author's transl)].

Authors:  S W Golf; V Graef; H Staudinger
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1974-12
  2 in total
  1 in total

1.  Effect of hexachlorobenzene on enzymes of the steroid metabolism in rat liver.

Authors:  V Graef; S W Golf; G Goerz
Journal:  Arch Toxicol       Date:  1979-12       Impact factor: 5.153
  1 in total

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