Literature DB >> 9763045

Folates in the periconceptional period: are women getting enough?

F Mathews1, P Yudkin, A Neil.   

Abstract

OBJECTIVE: To examine the prevalence of folic acid supplementation prior to conception and in the first trimester of pregnancy, and to identify sociodemographic variables associated with the use of supplements.
DESIGN: Observational study.
SETTING: District general hospital in the south in England. POPULATION: Nine hundred and sixty-three randomly selected pregnant nulliparous caucasian women recruited from May 1994 to February 1996 inclusive.
METHODS: Questionnaire administered at approximately 16 weeks gestation. MAIN OUTCOME MEASURES: Intakes of supplemental folic acid before conception and during pregnancy.
RESULTS: 31.5% (303/963) (95% CI 28.5-34.4) of pregnant women reported using supplements containing folic acid prior to conception. The proportion using pre-conceptional folic acid increased by approximately 1% per month during the 22 months of the study. 38.1% (367/962) (35 1 to 41.2) of women began taking folic acid only after the confirmation of pregnancy, and this proportion appeared constant over time. Young age, smoking and low educational attainment were statistically significant predictors of failure to use folic acid both before and during pregnancy.
CONCLUSIONS: Use of folic acid before conception in nulliparous women is much higher than the 2% to 3% reported in earlier studies of all pregnant women, and appears to be increasing. However, many women still only begin taking folic acid after conception, despite current health education strategies. New approaches, focusing on women who are currently least likely to take folic acid those who are young, are of low educational backgrounds, and are smokers - may now be required. Given the inevitably of unplanned pregnancies, efforts must also be made to increase the currently static uptake of folic acid immediately after the confirmation of pregnancy.

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Year:  1998        PMID: 9763045     DOI: 10.1111/j.1471-0528.1998.tb10257.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN: 0306-5456


  6 in total

1.  Neural tube defects and periconceptional folic acid in England and Wales: retrospective study.

Authors:  R A Kadir; C Sabin; B Whitlow; E Brockbank; D Economides
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2.  Pregnancy planning guide. Evidence-based information for prospective parents.

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3.  Pregnancy loss in lesbian and bisexual women: an online survey of experiences.

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4.  Nutrient intakes during pregnancy: the influence of smoking status and age.

Authors:  F Mathews; P Yudkin; R F Smith; A Neil
Journal:  J Epidemiol Community Health       Date:  2000-01       Impact factor: 3.710

5.  Folate during reproduction: the Canadian experience with folic acid fortification.

Authors:  Gillian Lindzon; Deborah L O'Connor
Journal:  Nutr Res Pract       Date:  2007-09-30       Impact factor: 1.926

6.  Folic acid knowledge and use among relatives in Irish families with neural tube defects: an intervention study.

Authors:  J Byrne
Journal:  Ir J Med Sci       Date:  2003 Jul-Sep       Impact factor: 1.568

  6 in total

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