| Literature DB >> 976016 |
Abstract
An in vivo system for the detection of sister chromatid exchange (SCE) in the central mudminnow, Umbra limi, is presented. Sister chromatid differential (SCD) and SCE were demonstrated by fluorescent and Giemsa procedures 5 to 6 days after the fish were injected with 500 mug/g of BrdU. The exchange rate was found to be 2.64 SCEs metaphase in the intestines and 2.42 SCEs/metaphase in the gills. SCE analysis in U. limi should be a useful tool for measuring the mutagenicity of water-borne chemicals.Entities:
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Year: 1976 PMID: 976016 DOI: 10.1007/BF00293110
Source DB: PubMed Journal: Chromosoma ISSN: 0009-5915 Impact factor: 4.316