Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Study of mitomycin C-induced chromosomal exchange.

Literature DB >> 976010

Study of mitomycin C-induced chromosomal exchange.

Abstract

Mitomycin C-induced sister chromatic exchange and quadriradial formation were studied in chromosomes from Muntiacus muntjac fibroblasts and A9, a transformed mouse cell line. We present the first direct cytological evidence for the induction of true somatic recombination involving homologous chromosomes. Analysis of the quadriradials from Muntjac cells indicates a non-random distribution with respect to the chromosomes involved and with respect to the points of conjunction. Sister chromatid exchange and quadriradial formation may reflect the outcome of repair processes involving a high frequency of homologous exchanges in the interphase nucleus.

Entities: Chemical Species

Mesh：

Substances：
Mitomycins

Year: 1976 PMID： 976010 DOI： 10.1007/BF00293724

Source DB: PubMed Journal: Chromosoma ISSN： 0009-5915 Impact factor: 4.316

20 in total

1. Actinomycin D effects on mitosis and chromosomes: sticky chromatids and localized lesions.

Authors: S Pathak; M McGill; T C Hsu
Journal: Chromosoma Date: 1975 Impact factor: 4.316

2. CHROMOSOME EXCHANGES IN HUMAN LEUKOCYTES INDUCED BY MITOMYCIN C.

Authors: M W SHAW; M M COHEN
Journal: Genetics Date: 1965-02 Impact factor: 4.562

3. The genetics of Aspergillus nidulans.

Authors: G PONTECORVO; J A ROPER; L M HEMMONS; K D MACDONALD; A W J BUFTON
Journal: Adv Genet Date: 1953 Impact factor: 1.944

4. Somatic Crossing over and Segregation in Drosophila Melanogaster.

Authors: C Stern
Journal: Genetics Date: 1936-11 Impact factor: 4.562

5. Sister chromatid exchanges induced by light flashes to 5-bromodeoxyuridine- and 5-iododeoxyuridine substituted Chinese hamster chromosomes.

Authors: T Ikushima; S Wolff
Journal: Exp Cell Res Date: 1974-07 Impact factor: 3.905

6. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Authors: S A Latt
Journal: Proc Natl Acad Sci U S A Date: 1973-12 Impact factor: 11.205

7. Sister chromatid exchanges induced in Chinese hamster cells by UV irradiation of different stages of the cell cycle: the necessity for cells to pass through S.

Authors: S Wolff; J Bodycote; R B Painter
Journal: Mutat Res Date: 1974-10 Impact factor: 2.433

5. Homologous recombination between overlapping thymidine kinase gene fragments stably inserted into a mouse cell genome.

Authors: F L Lin; N Sternberg
Journal: Mol Cell Biol Date: 1984-05 Impact factor: 4.272

6. Sister chromatid exchanges and heterochromatin.

Authors: I Schubert; R Rieger
Journal: Hum Genet Date: 1981 Impact factor: 4.132

Review 7. Mitotic crossing-over and segregation in man.

Authors: E Therman; E M Kuhn
Journal: Hum Genet Date: 1981 Impact factor: 4.132

Review 8. Sister chromatid exchange analysis.

Authors: S A Latt; R R Schreck
Journal: Am J Hum Genet Date: 1980-05 Impact factor: 11.025

9. Inhibition of carcinogen-induced chromosomal aberrations by an anticarcinogenic protease inhibitor.

Authors: A R Kinsella; M Radman
Journal: Proc Natl Acad Sci U S A Date: 1980-06 Impact factor: 11.205

10. Mitotic chiasmata and other quadriradials in mitomycin C-treated Bloom's syndrome lymphocytes.

Authors: E M Kuhn
Journal: Chromosoma Date: 1978-04-25 Impact factor: 4.316

Study of mitomycin C-induced chromosomal exchange.

1. Actinomycin D effects on mitosis and chromosomes: sticky chromatids and localized lesions.

2. CHROMOSOME EXCHANGES IN HUMAN LEUKOCYTES INDUCED BY MITOMYCIN C.

3. The genetics of Aspergillus nidulans.

4. Somatic Crossing over and Segregation in Drosophila Melanogaster.

5. Sister chromatid exchanges induced by light flashes to 5-bromodeoxyuridine- and 5-iododeoxyuridine substituted Chinese hamster chromosomes.

6. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

7. Sister chromatid exchanges induced in Chinese hamster cells by UV irradiation of different stages of the cell cycle: the necessity for cells to pass through S.

8. DNA repair and recombination.

9. Induction of sister chromatid exchanges by chemical mutagens and its possible relevance to DNA repair.

10. Differential Giemsa staining of sister chromatids and the study of chromatid exchanges without autoradiography.

1. Distribution of human chromosomes on the metaphase plate using banding techniques.

Review 2. Satellite DNA and heterochromatin variants: the case for unequal mitotic crossing over.

Review 3. Mutagenic effects of some anticancer antibiotics.