Literature DB >> 374224

Satellite DNA and heterochromatin variants: the case for unequal mitotic crossing over.

D M Kurnit.   

Abstract

Variations of constitutive heterochromatin (heteromorphisms) appear to be a general feature of eucaryotes. A variety of molecular and cytogenetic evidence supports the hypothesis that heteromorphisms result from unequal double-strand exchanges during mitotic DNA replication. Constitutive heterochromatin consists of highly repeated DNA sequences that are not transcribed. Thus, heteromorphisms are tolerated without overt phenotypic effect. Several of the highly repeated DNAs that comprise constitutive heterochromatin have been shown to contain site-specific endonuclease recognition sequences interspersed at regular intervals dependent upon nucleosome structure. These interspersed short repeated sequences could mediate unequal crossovers, resulting in quantitative variability of constitutive heterochromatin and satellite DNA. De novo variations of constitutive heterochromatin may be useful as markers of exposure to mutagens and/or carcinogens.

Mesh：

Substances：

Year:  1979        PMID： 374224     DOI： 10.1007/bf00273199

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  118 in total

1.  Long range periodicities in mouse satellite DNA.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-05-05       Impact factor: 5.469

2.  The repeat sequence of a hermit crab satellite deoxyribonucleic acid is (-T-A-G-G-)n-(-A-T-C-C-)n.

Authors:  D M Skinner; W G Beattie; F R Blattner; B P Stark; J E Dahlberg
Journal:  Biochemistry       Date:  1974-09-10       Impact factor: 3.162

3.  Heterochromatin, satellite DNA, and transformed neoplastic cells.

Authors:  N C Popescu; J A DiPaolo
Journal:  J Natl Cancer Inst       Date:  1972-08       Impact factor: 13.506

4.  Homologies of repetitive DNA sequences among Crustacea.

Authors:  D E Graham; D M Skinner
Journal:  Chromosoma       Date:  1973       Impact factor: 4.316

5.  Reptitive DNA sequences in drosophila.

Authors:  J G Gall; E H Cohen; M L Polan
Journal:  Chromosoma       Date:  1971       Impact factor: 4.316

6.  Formation and detection of RNA-DNA hybrid molecules in cytological preparations.

Authors:  J G Gall; M L Pardue
Journal:  Proc Natl Acad Sci U S A       Date:  1969-06       Impact factor: 11.205

7.  Partial sequence analysis of mouse satellite DNA evidence for short range periodicities.

Authors:  P A Biro; A Carr-Brown; E M Southern; P M Walker
Journal:  J Mol Biol       Date:  1975-05-05       Impact factor: 5.469

8.  Telomere associations in interphase nuclei of Allium cepa demonstrated by C-banding.

Authors:  C P Fussell
Journal:  Exp Cell Res       Date:  1977-11       Impact factor: 3.905

9.  Some properties of the single strands isolated from the DNA of the nuclear satellite of the mouse (Mus musculus).

Authors:  W G Flamm; P M Walker; M McCallum
Journal:  J Mol Biol       Date:  1969-03-28       Impact factor: 5.469

10.  Analysis of the alpha-satellite DNA from African green monkey cells by restriction nucleases.

Authors:  F Fittler
Journal:  Eur J Biochem       Date:  1977-04-01
View more
  36 in total

Review 1.  Twinning and mitotic crossing-over: some possibilities and their implications.

Authors:  G B Côté; J Gyftodimou
Journal:  Am J Hum Genet       Date:  1991-07       Impact factor: 11.025

2.  Inheritance of chromosome heteromorphisms analyzed by high-resolution bivariate flow karyotyping.

Authors:  B Trask; G van den Engh; J W Gray
Journal:  Am J Hum Genet       Date:  1989-11       Impact factor: 11.025

3.  Distribution of meiotic recombination along nondisjunction chromosomes 21 in Down syndrome determined using cytogenetics and RFLP haplotyping.

Authors:  H Meijer; G J Hamers; R J Jongbloed; G P Vaes-Peeters; R R van der Hulst; J P Geraedts
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

4.  Unequal homologous recombination between tandemly arranged sequences stably incorporated into cultured rat cells.

Authors:  J R Stringer; R M Kuhn; J L Newman; J C Meade
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

5.  A non-centromeric C band variant on chromosome 11q23.2.

Authors:  D K Spak; K Johnston; T A Donlon
Journal:  J Med Genet       Date:  1989-08       Impact factor: 6.318

6.  Chromosome heteromorphism quantified by high-resolution bivariate flow karyotyping.

Authors:  B Trask; G van den Engh; B Mayall; J W Gray
Journal:  Am J Hum Genet       Date:  1989-11       Impact factor: 11.025

7.  Molecular cytogenetic evidence for amplification of chromosome-specific alphoid sequences at enlarged C-bands on chromosome 6.

Authors:  E W Jabs; N Carpenter
Journal:  Am J Hum Genet       Date:  1988-07       Impact factor: 11.025

8.  Structure, organization, and sequence of alpha satellite DNA from human chromosome 17: evidence for evolution by unequal crossing-over and an ancestral pentamer repeat shared with the human X chromosome.

Authors:  J S Waye; H F Willard
Journal:  Mol Cell Biol       Date:  1986-09       Impact factor: 4.272

Review 9.  Chromosome 15 anomalies and the Prader-Willi syndrome: cytogenetic analysis.

Authors:  M G Mattei; N Souiah; J F Mattei
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

10.  Structural basis for Robertsonian translocations in man: association of ribosomal genes in the nucleolar fibrillar center in meiotic spermatocytes and oocytes.

Authors:  A Stahl; J M Luciani; M Hartung; M Devictor; J L Bergé-Lefranc; M Guichaoua
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.