| Literature DB >> 97525 |
B Rasmuson, H Svahlin, A Rasmuson, I Montell, H Olofsson.
Abstract
Somatic eye-colour mutations in an unstable genetic system, caused by a transposable element in the white locus of the X-chromosome in Drosophila melanogaster, is suggested as an assay system for mutagenicity testing. The system is evaluated by comparison with a corresponding system in a stable X-chromosome. Its sensitivity is confirmed with X-ray and EMS treatment, and it is found to be confined to the specific segment of the X-chromosome where the transposable element is localized.Entities:
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Year: 1978 PMID： 97525 DOI： 10.1016/0165-1161(78)90132-2
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433