Literature DB >> 9749445

Some controversies in planning and analysing multi-centre trials.

S Senn1.   

Abstract

It is shown that a rational approach to planning multi-centre trials will lead to an unequal distribution of patients across centres. Consequently different approaches to estimation will yield different estimates. However, some such approaches are not reasonable and it is concluded that multi-centre trials are less problematic than is commonly supposed.

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Mesh：

Year:  1998        PMID： 9749445     DOI： 10.1002/(sici)1097-0258(19980815/30)17:15/16<1753::aid-sim977>3.0.co;2-x

Source DB:  PubMed          Journal:  Stat Med        ISSN： 0277-6715            Impact factor:   2.373


  25 in total

1.  Design and analysis of controlled trials in naturally clustered environments: implications for medical informatics.

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2.  Bayesian modeling and prediction of accrual in multi-regional clinical trials.

Authors:  Yi Deng; Xiaoxi Zhang; Qi Long
Journal:  Stat Methods Med Res       Date:  2014-11-03       Impact factor: 3.021

3.  A Gaussian Copula Model for Multivariate Survival Data.

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Journal:  Stat Biosci       Date:  2010-12

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Journal:  J Neurosci       Date:  2010-08-11       Impact factor: 6.167

Review 5.  Clustering by health professional in individually randomised trials.

Authors:  Katherine J Lee; Simon G Thompson
Journal:  BMJ       Date:  2005-01-15

Review 6.  Valid statistical approaches for analyzing sholl data: Mixed effects versus simple linear models.

Authors:  Machelle D Wilson; Sunjay Sethi; Pamela J Lein; Kimberly P Keil
Journal:  J Neurosci Methods       Date:  2017-01-16       Impact factor: 2.390

Review 7.  Does patient volume affect clinical outcomes in adult intensive care units?

Authors:  Mrudula H Kanhere; Harsh A Kanhere; Alun Cameron; Guy J Maddern
Journal:  Intensive Care Med       Date:  2012-04-05       Impact factor: 17.440

8.  Data quality assurance and control in cognitive research: Lessons learned from the PREDICT-HD study.

Authors:  Holly James Westervelt; Rachel A Bernier; Melanie Faust; Mary Gover; H Jeremy Bockholt; Roland Zschiegner; Jeffrey D Long; Jane S Paulsen
Journal:  Int J Methods Psychiatr Res       Date:  2017-02-17       Impact factor: 4.035

9.  Bayesian accrual modeling and prediction in multicenter clinical trials with varying center activation times.

Authors:  Junhao Liu; Jo Wick; Yu Jiang; Matthew Mayo; Byron Gajewski
Journal:  Pharm Stat       Date:  2020-04-21       Impact factor: 1.894

10.  Design effect in multicenter studies: gain or loss of power?

Authors:  Emilie Vierron; Bruno Giraudeau
Journal:  BMC Med Res Methodol       Date:  2009-06-18       Impact factor: 4.615
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