Literature DB >> 9746386

Radical trachelectomy: a way to preserve fertility in the treatment of early cervical cancer.

J H Shepherd1, R A Crawford, D H Oram.   

Abstract

In the Centenary year of Wertheim's hysterectomy for the treatment of invasive cervical cancer, it is appropriate to look at less radical methods of managing early stage disease. Radical trachelectomy with pelvic lymphadenectomy is a conservative but locally radical procedure, preserving the corpus uteri and therefore fertility potential. The first 10 cases in a pilot study are presented. One patient has required post-operative radiotherapy and another a completion radical hysterectomy. Three live births by caesarean section and three other pregnancies have resulted. Careful selection within strict criteria may allow this more conservative approach without compromising cure. These procedures should be carried out in referral centres with continuing follow up and review.

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Year:  1998        PMID: 9746386     DOI: 10.1111/j.1471-0528.1998.tb10238.x

Source DB:  PubMed          Journal:  Br J Obstet Gynaecol        ISSN: 0306-5456


  10 in total

Review 1.  Review of neoadjuvant chemotherapy and trachelectomy: which cervical cancer patients would be suitable for neoadjuvant chemotherapy followed by fertility-sparing surgery?

Authors:  Helena Robova; Lukas Rob; Michael Jiri Halaska; Marek Pluta; Petr Skapa
Journal:  Curr Oncol Rep       Date:  2015       Impact factor: 5.075

Review 2.  Gynaecological cancer.

Authors:  H C Kitchener
Journal:  Postgrad Med J       Date:  1999-06       Impact factor: 2.401

Review 3.  Fertility-Sparing Options in Young Women with Cervical Cancer.

Authors:  Federica Tomao; Giacomo Corrado; Fedro Alessandro Peccatori; Sara Boveri; Eleonora Petra Preti; Nicoletta Colombo; Fabio Landoni
Journal:  Curr Treat Options Oncol       Date:  2016-01

4.  Challenging dogma: radical conservation surgery for early stage cervical cancer in order to retain fertility.

Authors:  John H Shepherd
Journal:  Ann R Coll Surg Engl       Date:  2009-04       Impact factor: 1.891

5.  Radical vaginal trachelectomy and laparoscopic pelvic lymphadenectomy in IB1 cervical cancer during pregnancy.

Authors:  Erasmo Bravo; Santiago Parry; Catalina Alonso; Sergio Rojas
Journal:  Gynecol Oncol Case Rep       Date:  2012-04-09

6.  Imaging of endometrial and cervical cancer.

Authors:  Shilpa Patel; Sidath H Liyanage; Anju Sahdev; Andrea G Rockall; Rodney H Reznek
Journal:  Insights Imaging       Date:  2010-09-28

7.  Less radical surgery for women with early stage cervical cancer: Our experience on radical vaginal trachelectomy and laparoscopic pelvic lymphadenectomy.

Authors:  I Rizzuto; W MacNab; R Nicholson; M Nalam; B Rufford
Journal:  Gynecol Oncol Rep       Date:  2019-03-11

8.  Fertility-sparing surgery for early-stage cervical cancer.

Authors:  Adelaide Fernanda Ribeiro Cubal; Joana Isabel Ferreira Carvalho; Maria Fernanda Martins Costa; Ana Paula Tavares Branco
Journal:  Int J Surg Oncol       Date:  2012-07-08

Review 9.  Surgical treatment of stage IA2 cervical cancer.

Authors:  Fani Kokka; Andrew Bryant; Elly Brockbank; Arjun Jeyarajah
Journal:  Cochrane Database Syst Rev       Date:  2014-05-29

10.  Radical vaginal trachelectomy at 16 weeks' gestation: A case report.

Authors:  D F Kolomainen; R J Bradley; P Larsen-Disney; J H Shepherd
Journal:  Gynecol Oncol Case Rep       Date:  2013-03-14
  10 in total

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