Literature DB >> 973905

Diazepam in acute myocardial infarction. Clinical effects and effects on catecholamines, free fatty acids, and cortisol.

M Melsom, P Andreassen, H Melsom, T Hansen, H Grendahl, L K Hillestad.   

Abstract

Diazepam is a valuable drug in cases of acute myocardial infarction. The 10 mg intravenous loading dose and the subsequent 15 mg oral dose of diazepam administered three times daily produced safe, pleasant sedation, and reduced the need for analgesics. A much reduced excretion of catecholamines was recorded. It is presumed that diazepam causes a lower stress reaction, which is beneficial in diminishing the incidence of malignant arrhythmias and preventing the existing myocardial injury from spreading.

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Year:  1976        PMID: 973905      PMCID: PMC483091          DOI: 10.1136/hrt.38.8.804

Source DB:  PubMed          Journal:  Br Heart J        ISSN: 0007-0769


  8 in total

1.  Psychopharmacological management of post-myocardial depression and anxiety.

Authors:  R C Monks
Journal:  Can Fam Physician       Date:  1981-07       Impact factor: 3.275

Review 2.  Minor tranquillizers in somatic disorders.

Authors:  C Krogh; W M McLean; Y D LaPierre
Journal:  Can Med Assoc J       Date:  1978-05-06       Impact factor: 8.262

3.  Cortisol response to diazepam: its relationship to age, dose, duration of treatment, and presence of generalized anxiety disorder.

Authors:  Nunzio Pomara; Lisa M Willoughby; John J Sidtis; Thomas B Cooper; David J Greenblatt
Journal:  Psychopharmacology (Berl)       Date:  2004-08-27       Impact factor: 4.530

4.  The measurement and control of myocardial infarct size.

Authors:  M C Apps; J Tinker
Journal:  Intensive Care Med       Date:  1978-01       Impact factor: 17.440

5.  Diazepam in immediate post-myocardial infarct period. A double blind trial.

Authors:  R A Dixon; I R Edwards; J Pilcher
Journal:  Br Heart J       Date:  1980-05

6.  Effect of flunitrazepam as an oral hypnotic on 24-hour blood pressure in healthy volunteers.

Authors:  Daniele Bosone; Roberto Fogari; Annalisa Zoppi; Angela D'Angelo; Natascia Ghiotto; Giulia Perini; Matteo Cotta Ramusino; Alfredo Costa
Journal:  Eur J Clin Pharmacol       Date:  2018-04-30       Impact factor: 2.953

7.  Diazepam ameliorated myocardial ischemia-reperfusion injury via inhibition of C-C chemokine receptor type 2/tumor necrosis factor-alpha/interleukins and Bcl-2-associated X protein/caspase-3 pathways in experimental rats.

Authors:  Tingting Jiang; Xinghua Ma; Huimin Chen; Hongfeng Jia; Ying Xiong
Journal:  J Vet Med Sci       Date:  2021-11-01       Impact factor: 1.267

8.  Phosphoglycerate mutase 2 is elevated in serum of patients with heart failure and correlates with the disease severity and patient's prognosis.

Authors:  Min Li; Xiaoyuan Gao; Huiyun Wang; Mingli Zhang; Xiaoying Li; Shuya Wang; Shaoqin Wang; Chongfeng Cao; Ying Li; Guohai Su
Journal:  Open Med (Wars)       Date:  2021-08-11
  8 in total

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