Literature DB >> 9729423

Gene expression of the P2X receptors in the rat retina.

U Brändle1, E Guenther, C Irrle, T H Wheeler-Schilling.   

Abstract

Molecular-biological methods were used to demonstrate the expression of six P2X receptor subunits (P2X1-P2X6) in retina and choroid. Despite the considerable evidence for signalling by extracellular nucleotides in other sensory systems, few studies have been undertaken in the eye. RT-PCR for the detection of P2X subunit mRNA in the rat of different postnatal developmental stages (P23-P210) revealed the presence of P2X2 and P2X4 mRNA in the retina and choroid; P2X3, and P2X5 were detected only in the retina. There was no evidence for P2X1 and P2X6 mRNA in the ocular tissue under investigation. Our data suggest that extracellular ATP may have influences on visual processing. Copyright 1998 Elsevier Science B.V.

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Year:  1998        PMID： 9729423     DOI： 10.1016/s0169-328x(98)00159-4

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  12 in total

1.  P2X7 receptors in Müller glial cells from the human retina.

Authors:  T Pannicke; W Fischer; B Biedermann; H Schädlich; J Grosche; F Faude; P Wiedemann; C Allgaier; P Illes; G Burnstock; A Reichenbach
Journal:  J Neurosci       Date:  2000-08-15       Impact factor: 6.167

2.  Distribution and development of P2Y1-purinoceptors in the mouse retina.

Authors:  Rai Dilip; Toshiyuki Ishii; Hideki Imada; Yuko Wada-Kiyama; Ryoiti Kiyama; Eiichi Miyachi; Makoto Kaneda
Journal:  J Mol Histol       Date:  2013-08-02       Impact factor: 2.611

Review 3.  Activation and regulation of purinergic P2X receptor channels.

Authors:  Claudio Coddou; Zonghe Yan; Tomas Obsil; J Pablo Huidobro-Toro; Stanko S Stojilkovic
Journal:  Pharmacol Rev       Date:  2011-07-07       Impact factor: 25.468

4.  Ca2+-permeable P2X receptor channels in cultured rat retinal ganglion cells.

Authors:  H Taschenberger; R Jüttner; R Grantyn
Journal:  J Neurosci       Date:  1999-05-01       Impact factor: 6.167

Review 5.  P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.

Authors:  Gary A Weisman; Jean M Camden; Troy S Peterson; Deepa Ajit; Lucas T Woods; Laurie Erb
Journal:  Mol Neurobiol       Date:  2012-04-01       Impact factor: 5.590

Review 6.  Purinergic signaling in the retina: From development to disease.

Authors:  Ana Lucia Marques Ventura; Alexandre Dos Santos-Rodrigues; Claire H Mitchell; Maria Paula Faillace
Journal:  Brain Res Bull       Date:  2018-11-17       Impact factor: 4.077

7.  Saffron reduces ATP-induced retinal cytotoxicity by targeting P2X7 receptors.

Authors:  Lucia Corso; Anna Cavallero; Debora Baroni; Patrizia Garbati; Gianfranco Prestipino; Silvia Bisti; Mario Nobile; Cristiana Picco
Journal:  Purinergic Signal       Date:  2016-01-07       Impact factor: 3.765

Review 8.  Purinergic signalling during development and ageing.

Authors:  Geoffrey Burnstock; Nicholas Dale
Journal:  Purinergic Signal       Date:  2015-05-20       Impact factor: 3.765

9.  Hyaluronan fragments improve wound healing on in vitro cutaneous model through P2X7 purinoreceptor basal activation: role of molecular weight.

Authors:  Kamelia Ghazi; Uriell Deng-Pichon; Jean-Michel Warnet; Patrice Rat
Journal:  PLoS One       Date:  2012-11-16       Impact factor: 3.240

10.  How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina.

Authors:  Ivan Tochitsky; Zachary Helft; Victor Meseguer; Russell B Fletcher; Kirstan A Vessey; Michael Telias; Bristol Denlinger; Jonatan Malis; Erica L Fletcher; Richard H Kramer
Journal:  Neuron       Date:  2016-09-22       Impact factor: 18.688
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