Literature DB >> 9725763

Early growth response factor 1: a pleiotropic mediator of inducible gene expression.

L M Khachigian1, T Collins.   

Abstract

The zinc-finger transcription factor, early growth response factor-1 (Egr-1) is an immediate-early gene product inducibly expressed in response to diverse stimuli. This review examines the emerging role of Egr-1 in vascular pathobiology.

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Year:  1998        PMID： 9725763     DOI： 10.1007/s001090050258

Source DB:  PubMed          Journal:  J Mol Med (Berl)        ISSN： 0946-2716            Impact factor:   4.599


  26 in total

Review 1.  Pathways of Egr-1-mediated gene transcription in vascular biology.

Authors:  E S Silverman; T Collins
Journal:  Am J Pathol       Date:  1999-03       Impact factor: 4.307

2.  Influence of sustained mechanical stress on Egr-1 mRNA expression in cultured human endothelial cells.

Authors:  M Stula; H D Orzechowski; S Gschwend; R Vetter; R von Harsdorf; R Dietz; M Paul
Journal:  Mol Cell Biochem       Date:  2000-07       Impact factor: 3.396

3.  KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells.

Authors:  Sudha Mannava; DaZhong Zhuang; Jayakumar R Nair; Rajat Bansal; Joseph A Wawrzyniak; Shoshanna N Zucker; Emily E Fink; Kalyana C Moparthy; Qiang Hu; Song Liu; Lawrence H Boise; Kelvin P Lee; Mikhail A Nikiforov
Journal:  Blood       Date:  2011-12-05       Impact factor: 22.113

Review 4.  Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy.

Authors:  Swati Bhattacharyya; Minghua Wu; Feng Fang; Warren Tourtellotte; Carol Feghali-Bostwick; John Varga
Journal:  Matrix Biol       Date:  2011-04-13       Impact factor: 11.583

Review 5.  Egr-1 is a major vascular pathogenic transcription factor in atherosclerosis and restenosis.

Authors:  Florian Blaschke; Dennis Bruemmer; Ronald E Law
Journal:  Rev Endocr Metab Disord       Date:  2004-08       Impact factor: 6.514

6.  Calcipotriol affects keratinocyte proliferation by decreasing expression of early growth response-1 and polo-like kinase-2.

Authors:  Jernej Kristl; Petra Slanc; Metka Krasna; Ales Berlec; Matjaz Jeras; Borut Strukelj
Journal:  Pharm Res       Date:  2007-08-02       Impact factor: 4.200

Review 7.  Transcriptional regulation of the intestinal luminal Na⁺ and Cl⁻ transporters.

Authors:  Jaleh Malakooti; Seema Saksena; Ravinder K Gill; Pradeep K Dudeja
Journal:  Biochem J       Date:  2011-04-15       Impact factor: 3.857

8.  Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active.

Authors:  Takashi Shimada; Itaru Urakawa; Tamara Isakova; Yuji Yamazaki; Michael Epstein; Katherine Wesseling-Perry; Myles Wolf; Isidro B Salusky; Harald Jüppner
Journal:  J Clin Endocrinol Metab       Date:  2009-12-04       Impact factor: 5.958

9.  The transcriptional cofactor nab2 is induced by tgf-Beta and suppresses fibroblast activation: physiological roles and impaired expression in scleroderma.

Authors:  Swati Bhattacharyya; Jun Wei; Denisa S Melichian; Jeffrey Milbrandt; Kazuhiko Takehara; John Varga
Journal:  PLoS One       Date:  2009-10-26       Impact factor: 3.240

10.  Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth.

Authors:  Roger G Fahmy; Levon M Khachigian
Journal:  Nucleic Acids Res       Date:  2004-04-23       Impact factor: 16.971
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