Literature DB >> 15211096

Egr-1 is a major vascular pathogenic transcription factor in atherosclerosis and restenosis.

Florian Blaschke1, Dennis Bruemmer, Ronald E Law.   

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Year:  2004        PMID： 15211096     DOI： 10.1023/B:REMD.0000032413.88756.ee

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


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Review 2.  Pharmacology of smooth muscle cell replication.

Authors:  C L Jackson; S M Schwartz
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3.  Inducible PDGF A-chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3.

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Journal:  Am J Physiol       Date:  1997-09

Review 4.  The biology of restenosis.

Authors:  C Bauters; J M Isner
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5.  Regrowth of arterial endothelium. Denudation with minimal trauma leads to complete endothelial cell regrowth.

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6.  Left main coronary artery stenosis as a late complication of percutaneous transluminal coronary angioplasty.

Authors:  N Hamad; A Pichard; A Oboler; J Lindsay
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7.  A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.

Authors:  A L Gashler; S Swaminathan; V P Sukhatme
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

8.  TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.

Authors:  A P Vicari; D J Figueroa; J A Hedrick; J S Foster; K P Singh; S Menon; N G Copeland; D J Gilbert; N A Jenkins; K B Bacon; A Zlotnik
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9.  Novel gp91(phox) homologues in vascular smooth muscle cells : nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways.

Authors:  B Lassègue; D Sorescu; K Szöcs; Q Yin; M Akers; Y Zhang; S L Grant; J D Lambeth; K K Griendling
Journal:  Circ Res       Date:  2001-05-11       Impact factor: 17.367

10.  A regulatory element in the human interleukin 2 gene promoter is a binding site for the zinc finger proteins Sp1 and EGR-1.

Authors:  C Skerka; E L Decker; P F Zipfel
Journal:  J Biol Chem       Date:  1995-09-22       Impact factor: 5.157
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1.  In vivo differences between endothelial transcriptional profiles of coronary and iliac arteries revealed by microarray analysis.

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Review 2.  Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system.

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Review 3.  Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury.

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Journal:  Curr Atheroscler Rep       Date:  2006-05       Impact factor: 5.113

4.  Aortic smooth muscle cell alterations in mice systemically exposed to arsenic.

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5.  Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury.

Authors:  Kae-Woei Liang; Chih-Tai Ting; Sui-Chu Yin; Ying-Tsung Chen; Shing-Jong Lin; James K Liao; Shih-Lan Hsu
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6.  Targeting of metallothionein by L-homocysteine: a novel mechanism for disruption of zinc and redox homeostasis.

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7.  Vasopressin up-regulates the expression of growth-related immediate-early genes via two distinct EGF receptor transactivation pathways.

Authors:  Lida Q Fuentes; Carlos E Reyes; José M Sarmiento; Carolina I Villanueva; Carlos D Figueroa; Javier Navarro; Carlos B González
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8.  Histamine induces Egr-1 expression in human aortic endothelial cells via the H1 receptor-mediated protein kinase Cdelta-dependent ERK activation pathway.

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Journal:  J Biol Chem       Date:  2008-08-05       Impact factor: 5.157

9.  Egr-1 upregulates OPN through direct binding to its promoter and OPN upregulates Egr-1 via the ERK pathway.

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10.  Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells.

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