PURPOSE: To determine whether diffusion-weighted echo-planar magnetic resonance (MR) imaging can help differentiate mucin-producing tumors of the pancreas from other cystic lesions. MATERIALS AND METHODS: Diffusion-weighted echo-planar 1.5-T MR imaging was performed in patients with mucin-producing tumor (n = 15), pseudocyst (n = 15), or serous microcystic tumor (n = 2). Images were obtained with diffusion-sensitizing gradients of 30 and 300 sec/mm2. The apparent diffusion coefficient (ADC) was calculated. RESULTS: At 30 sec/mm2, all cystic lesions had very high signal intensity. The dilated main pancreatic duct was depicted in eight patients with mucin-producing tumor and in six with pseudocyst. The mean (+/- standard deviation) ADCs of mucin-producing tumors (2.7 x 10(-3) mm2/sec +/- 0.9 x 10(-3)) and pseudocysts (3.2 x 10(-3) mm2/sec +/- 1.0 x 10(-3) were significantly lower (P < .01) than those of serous cysts or cerebrospinal fluid (5.8 x 10(-3) mm2/sec +/- 2.0 x 10(-3)). At 300 sec/mm2, cysts and the main pancreatic ducts had high signal intensity in cases of mucin-producing tumor, indicative of the presence of mucinous products in both the cystic cavity and the main pancreatic duct. The signal intensity of cystic fluid in pseudocysts was high on diffusion-weighted images, but that of the pancreatic duct was decreased (ADC = 5.1 x 10(-3) mm2/sec +/- 1.7 x 10(-3)). CONCLUSION: Diffusion-weighted MR imaging can help characterize cystic lesions of the pancreas. Findings-suggestive of viscous fluid in mucin-producing tumors are present on such images.
PURPOSE: To determine whether diffusion-weighted echo-planar magnetic resonance (MR) imaging can help differentiate mucin-producing tumors of the pancreas from other cystic lesions. MATERIALS AND METHODS: Diffusion-weighted echo-planar 1.5-T MR imaging was performed in patients with mucin-producing tumor (n = 15), pseudocyst (n = 15), or serous microcystic tumor (n = 2). Images were obtained with diffusion-sensitizing gradients of 30 and 300 sec/mm2. The apparent diffusion coefficient (ADC) was calculated. RESULTS: At 30 sec/mm2, all cystic lesions had very high signal intensity. The dilated main pancreatic duct was depicted in eight patients with mucin-producing tumor and in six with pseudocyst. The mean (+/- standard deviation) ADCs of mucin-producing tumors (2.7 x 10(-3) mm2/sec +/- 0.9 x 10(-3)) and pseudocysts (3.2 x 10(-3) mm2/sec +/- 1.0 x 10(-3) were significantly lower (P < .01) than those of serous cysts or cerebrospinal fluid (5.8 x 10(-3) mm2/sec +/- 2.0 x 10(-3)). At 300 sec/mm2, cysts and the main pancreatic ducts had high signal intensity in cases of mucin-producing tumor, indicative of the presence of mucinous products in both the cystic cavity and the main pancreatic duct. The signal intensity of cystic fluid in pseudocysts was high on diffusion-weighted images, but that of the pancreatic duct was decreased (ADC = 5.1 x 10(-3) mm2/sec +/- 1.7 x 10(-3)). CONCLUSION: Diffusion-weighted MR imaging can help characterize cystic lesions of the pancreas. Findings-suggestive of viscous fluid in mucin-producing tumors are present on such images.
Authors: J L Evelhoch; R J Gillies; G S Karczmar; J A Koutcher; R J Maxwell; O Nalcioglu; N Raghunand; S M Ronen; B D Ross; H M Swartz Journal: Neoplasia Date: 2000 Jan-Apr Impact factor: 5.715
Authors: Chiara Pozzessere; Sandra Luz Castaños Gutiérrez; Celia Pamela Corona-Villalobos; Lorenzo Righi; Chunmiao Xu; Anne Marie Lennon; Christopher L Wolfgang; Ralph H Hruban; Michael Goggins; Marcia I Canto; Ihab R Kamel Journal: J Comput Assist Tomogr Date: 2016 Jul-Aug Impact factor: 1.826