Literature DB >> 972227

Alkylation of polyguanylic acid at the 2-amino group and phosphate by the potent mutagen (+/-)-7beta,8alpha-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

M Koreeda, P D Moore, H Yagi, H J Yeh, D M Jerina.   

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Year:  1976        PMID: 972227     DOI: 10.1021/ja00437a061

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  13 in total

1.  Excision repair of benzo[a]pyrene-deoxyguanosine adducts in baby hamster kidney 21/C13 cells and in secondary mouse embryo fibroblasts C57BL/6J.

Authors:  K Shinohara; P A Cerutti
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

Review 2.  Metabolism and activation of chemical carcinogens.

Authors:  E K Weisburger
Journal:  Mol Cell Biochem       Date:  1980-09-15       Impact factor: 3.396

Review 3.  Nucleic acid adducts of chemical carcinogens and mutagens.

Authors:  K Hemminki
Journal:  Arch Toxicol       Date:  1983-04       Impact factor: 5.153

4.  Benzo[a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate.

Authors:  T Meehan; A R Wolfe; G R Negrete; Q Song
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

5.  Hydrolysis of benzo[a]pyrene diol epoxide and its covalent binding to DNA proceed through similar rate-determining steps.

Authors:  T Meehan; D M Bond
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

6.  Chloride ions catalyze the formation of cis adducts in the binding of anti-benzo[a]pyrene diol epoxide to nucleic acids.

Authors:  A R Wolfe; J Yamamoto; T Meehan
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-15       Impact factor: 11.205

7.  Immunohistochemical detection of anti-(+/-)-trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)p yrene-bound adduct in nuclei of cultured HeLa cells and mouse lung tissue.

Authors:  N Nemoto; Y Nakatsuru; K Nakagawa; A Tazawa; T Ishikawa
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

8.  Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides.

Authors:  A W Wood; R L Chang; W Levin; R E Lehr; M Schaefer-Ridder; J M Karle; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

9.  Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro.

Authors:  K M Straub; T Meehan; A L Burlingame; M Calvin
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

Authors:  M Cosman; C de los Santos; R Fiala; B E Hingerty; S B Singh; V Ibanez; L A Margulis; D Live; N E Geacintov; S Broyde
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

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