Literature DB >> 9719493

Estrogen-mediated immunosuppression in autoimmune diseases.

L Jansson1, R Holmdahl.   

Abstract

Gender affects the susceptibility to many autoimmune diseases. Women have an increased risk of developing diseases such as rheumatoid arthritis and multiple sclerosis compared with men. The female preponderance is believed to depend in part on the influence of sex hormones on the immune system. The mechanism of estrogen-induced immune suppression both in human autoimmune diseases and their experimental animal model counterparts is discussed. In addition, the mechanisms of estrogen and anti-estrogens are discussed in relation to their possible use as future therapeutic anti-inflammatory agents.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9719493     DOI： 10.1007/s000110050332

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


  32 in total

Review 1.  The selective oestrogen receptor modulation: evolution and clinical applications.

Authors:  D W Purdie; S A Beardsworth
Journal:  Br J Clin Pharmacol       Date:  1999-12       Impact factor: 4.335

Review 2.  The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation.

Authors:  Valentin A Pavlov; Hong Wang; Christopher J Czura; Steven G Friedman; Kevin J Tracey
Journal:  Mol Med       Date:  2003 May-Aug       Impact factor: 6.354

3.  Differences in host susceptibility to disease progression in the human challenge model of Haemophilus ducreyi infection.

Authors:  Stanley M Spinola; Cliffton T H Bong; Andrew L Faber; Kate R Fortney; Stacy L Bennett; Carisa A Townsend; Beth E Zwickl; Steven D Billings; Tricia L Humphreys; Margaret E Bauer; Barry P Katz
Journal:  Infect Immun       Date:  2003-11       Impact factor: 3.441

4.  Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.

Authors:  Simone Cenci; Gianluca Toraldo; M Neale Weitzmann; Cristiana Roggia; Yuhao Gao; Wei Ping Qian; Oscar Sierra; Roberto Pacifici
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-15       Impact factor: 11.205

Review 5.  Strain-Related Differences in the Immune Response: Relevance to Human Stroke.

Authors:  Kyra J Becker
Journal:  Transl Stroke Res       Date:  2016-02-10       Impact factor: 6.829

6.  Oestrogen-mediated protection of experimental autoimmune encephalomyelitis in the absence of Foxp3+ regulatory T cells implicates compensatory pathways including regulatory B cells.

Authors:  Sandhya Subramanian; Melissa Yates; Arthur A Vandenbark; Halina Offner
Journal:  Immunology       Date:  2010-11-23       Impact factor: 7.397

Review 7.  Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases.

Authors:  Elisabetta Vegeto; Valeria Benedusi; Adriana Maggi
Journal:  Front Neuroendocrinol       Date:  2008-04-29       Impact factor: 8.606

Review 8.  B cells as effectors and regulators of sex-biased arthritis.

Authors:  David Luckey; Kay Medina; Veena Taneja
Journal:  Autoimmunity       Date:  2012-08       Impact factor: 2.815

9.  T lymphocytes do not directly mediate the protective effect of estrogen on experimental autoimmune encephalomyelitis.

Authors:  Magdalena J Polanczyk; Richard E Jones; Sandhya Subramanian; Michael Afentoulis; Cathleen Rich; Melissa Zakroczymski; Paul Cooke; Arthur A Vandenbark; Halina Offner
Journal:  Am J Pathol       Date:  2004-12       Impact factor: 4.307

10.  Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome.

Authors:  Gil-Jin Shim; Margaret Warner; Hyun-Jin Kim; Sandra Andersson; Lining Liu; Jenny Ekman; Otabek Imamov; Margaret E Jones; Evan R Simpson; Jan-Ake Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2004-08-16       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.