Literature DB >> 9704404

Endocytosis proteins and cancer: a potential link?

S Floyd1, P De Camilli.   

Abstract

Recent studies have shown that a variety of proteins participate with clathrin and clathrin adaptors in receptor-mediated endocytosis. The genes encoding some of these proteins are targets of chromosomal rearrangements in human haematopoietic malignancies. In addition, abnormal expression or mutation of some endocytosis proteins has been reported in human cancers. This article discusses these observations and elaborates the potential mechanisms by which the abnormal expression of endocytosis proteins might participate in the biology of cancer.

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Year:  1998        PMID： 9704404     DOI： 10.1016/s0962-8924(98)01316-6

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  26 in total

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