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Literature DB >> 969919

SH Reactivity of cigarette smoke and its correlation with carcinogenic effects on hamster lung cultures.

C Leuchtenberger, R Leuchtenberger, I Zbinden, E Schleh.

Abstract

After hamster lung cultures were exposed repeatedly to puffs of fresh smoke from 7 types of cigarettes containing variable amounts of particulate and gas vapour phase components, atypical growth and/or malignant cell transformation were observed within a period of 3-6 months. A positive correlation was demonstrable between high SH reactivity and high NO content of the gas vapour phase and malignant transformation. There was no positive correlation for the other analyzed components of the smoke, including tar content.

Entities: Disease Species

Mesh：

Substances：

Year: 1976 PMID： 969919 DOI： 10.1007/BF01994377

Source DB: PubMed Journal: Soz Praventivmed ISSN： 0303-8408

10 in total

1. Differential response of Snell's and C57 black mice to chronic inhalation of cigarette smoke. Pulmonary carcinogenesis and vascular alterations in lung and heart.

Authors: C Leuchtenberger; R Leuchtenberger
Journal: Oncology Date: 1974 Impact factor: 2.935

2. Gas vapour phase constituents and SH reactivity of cigarette smoke influence lung cultures.

Authors: C Leuchtenberger; R Leuchtenberger; I Zbinden
Journal: Nature Date: 1974-02-22 Impact factor: 49.962

3. Differential cytological and cytochemical responses of various cultures from mouse tissues to repeated exposres to puffs from the gas phase of charcoal-filtered fresh cigarette smoke.

Authors: C Leuchtenberger; R Leuchtenberger
Journal: Exp Cell Res Date: 1970-09 Impact factor: 3.905

10. The mechanism of carcinogenesis by tobacco smoke. Further experimental evidence and a prediction from the thiol-defence hypothesis.

Authors: M L Fenner; J Braven
Journal: Br J Cancer Date: 1968-09 Impact factor: 7.640

10 in total

4 in total

1. Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke.

Authors: Norbert Staimer; Tran B Nguyen; Sergey A Nizkorodov; Ralph J Delfino
Journal: Anal Bioanal Chem Date: 2012-02-21 Impact factor: 4.142

2. Comparison of protection by L-ascorbic acid, L-cysteine, and adrenergic-blocking agents against acetaldehyde, acrolein, and formaldehyde toxicity: implications in smoking.

Authors: H Sprince; C M Parker; G G Smith
Journal: Agents Actions Date: 1979-10

3. Protection of hamster lung cultures by L-cysteine or vitamin C against carcinogenic effects of fresh smoke from tobacco or marihuana cigarettes.

Authors: C Leuchtenberger; R Leuchtenberger
Journal: Br J Exp Pathol Date: 1977-12

4. Free-radical chemistry of cigarette smoke and its toxicological implications.

Authors: D F Church; W A Pryor
Journal: Environ Health Perspect Date: 1985-12 Impact factor: 9.031

4 in total

SH Reactivity of cigarette smoke and its correlation with carcinogenic effects on hamster lung cultures.

1. Differential response of Snell's and C57 black mice to chronic inhalation of cigarette smoke. Pulmonary carcinogenesis and vascular alterations in lung and heart.

2. Gas vapour phase constituents and SH reactivity of cigarette smoke influence lung cultures.

3. Differential cytological and cytochemical responses of various cultures from mouse tissues to repeated exposres to puffs from the gas phase of charcoal-filtered fresh cigarette smoke.

4. Effects of marijuana and tobacco smoke on human lung physiology.

5. Effects of marijuana and tobacco smoke on DNA and chromosomal complement in human lung explants.

6. Cigarette smoke--a proposed metabolic lesion in alveolar macrophages.

7. Tumor rejection in experimental animals treated with radioprotective thiols.

8. Cigarette Smoke: Mode of Adhesion and Haemolyzing and SH-inhibiting Factors.

9. Inhibiting effect of tobacco smoke on some crystalline enzymes.

10. The mechanism of carcinogenesis by tobacco smoke. Further experimental evidence and a prediction from the thiol-defence hypothesis.

1. Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke.

2. Comparison of protection by L-ascorbic acid, L-cysteine, and adrenergic-blocking agents against acetaldehyde, acrolein, and formaldehyde toxicity: implications in smoking.

3. Protection of hamster lung cultures by L-cysteine or vitamin C against carcinogenic effects of fresh smoke from tobacco or marihuana cigarettes.

4. Free-radical chemistry of cigarette smoke and its toxicological implications.