Literature DB >> 13758816

Inhibiting effect of tobacco smoke on some crystalline enzymes.

R LANGE.   

Abstract

Tobacco smoke absorbed in phosphate buffer at neutral pH inhibits irreversibly the enzymes rabbit muscle glyceraldehyde-3-phosphate dehydrogenase and yeast alcohol dehydrogenase, whereas lactic dehydrogenase and glutamic dehydrogenase are not inhibited. A transient inhibition of beef liver catalase occurs. Indirect evidence suggests that the observed enzyme inhibition is caused by peroxides present in the smoke.

Entities:  

Keywords:  DEHYDROGENASES/antagonists; TOBACCO

Mesh：

Substances：

Year:  1961        PMID： 13758816     DOI： 10.1126/science.134.3471.52

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Inhibition of growth and respiration of yeast (Saccharomyces carlsbergensis) by tobacco smoke condensate and its fraction.

Authors:  C Gairola; M I Aleem
Journal:  Experientia       Date:  1975-03-15

2.  SH Reactivity of cigarette smoke and its correlation with carcinogenic effects on hamster lung cultures.

Authors:  C Leuchtenberger; R Leuchtenberger; I Zbinden; E Schleh
Journal:  Soz Praventivmed       Date:  1976 Jan-Feb

3.  Complexity of enzymatic inhibition by cigarette smoke.

Authors:  R C Benedict; R L Stedman
Journal:  Experientia       Date:  1968-12-15

4.  Protection of hamster lung cultures by L-cysteine or vitamin C against carcinogenic effects of fresh smoke from tobacco or marihuana cigarettes.

Authors:  C Leuchtenberger; R Leuchtenberger
Journal:  Br J Exp Pathol       Date:  1977-12

5.  Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract.

Authors:  M Yokode; T Kita; H Arai; C Kawai; S Narumiya; M Fujiwara
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

6.  Free-radical chemistry of cigarette smoke and its toxicological implications.

Authors:  D F Church; W A Pryor
Journal:  Environ Health Perspect       Date:  1985-12       Impact factor: 9.031
  6 in total

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