E T Donnelly1, S E Lewis, J A McNally, W Thompson. 1. Department of Obstetrics and Gynaecology, The Queen's University of Belfast, Northern Ireland. e.donnelly@qub.ac.uk
Abstract
OBJECTIVE: To determine the relationship between sperm motility and sperm morphology parameters and IVF and pregnancy rates. DESIGN: Pre- and postpreparation analysis of semen samples from infertile couples undergoing IVF-ET. SETTING: Andrology Laboratory, Royal Maternity Hospital, Belfast, Northern Ireland. PATIENT(S): One hundred fifty couples undergoing IVF-ET treatment at the Regional Fertility Centre. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The ability of human sperm to achieve IVF and pregnancy was investigated in relation to motility parameters (assessed with computer-aided sperm analysis [Integrated Visual Optical System] and percent normal morphology (determined with the strict criteria). RESULT(S): Significant differences were observed in motility parameters and percent normal morphology in samples that achieved > or =50% fertilization compared with < or =50% fertilization and between samples that achieved a pregnancy compared with those that did not. Significant positive correlations were observed between percent progressive motility, the velocity of sperm movement, and morphology parameters and both IVF and pregnancy. CONCLUSION(S): Both sperm motility parameters and percent normal morphology are significant factors in predicting fertilization and pregnancy rates in IVF.
OBJECTIVE: To determine the relationship between sperm motility and sperm morphology parameters and IVF and pregnancy rates. DESIGN: Pre- and postpreparation analysis of semen samples from infertile couples undergoing IVF-ET. SETTING: Andrology Laboratory, Royal Maternity Hospital, Belfast, Northern Ireland. PATIENT(S): One hundred fifty couples undergoing IVF-ET treatment at the Regional Fertility Centre. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The ability of human sperm to achieve IVF and pregnancy was investigated in relation to motility parameters (assessed with computer-aided sperm analysis [Integrated Visual Optical System] and percent normal morphology (determined with the strict criteria). RESULT(S): Significant differences were observed in motility parameters and percent normal morphology in samples that achieved > or =50% fertilization compared with < or =50% fertilization and between samples that achieved a pregnancy compared with those that did not. Significant positive correlations were observed between percent progressive motility, the velocity of sperm movement, and morphology parameters and both IVF and pregnancy. CONCLUSION(S): Both sperm motility parameters and percent normal morphology are significant factors in predicting fertilization and pregnancy rates in IVF.
Authors: Summer G Goodson; Sarah White; Alicia M Stevans; Sanjana Bhat; Chia-Yu Kao; Scott Jaworski; Tamara R Marlowe; Martin Kohlmeier; Leonard McMillan; Steven H Zeisel; Deborah A O'Brien Journal: Biol Reprod Date: 2017-11-01 Impact factor: 4.285
Authors: Aramandla Ramesh; Frank Inyang; Donald D Lunstra; Mohammad S Niaz; Prapaporn Kopsombut; Kea M Jones; Daryl B Hood; Edward R Hills; Anthony E Archibong Journal: Exp Toxicol Pathol Date: 2008-05-21
Authors: Kea M Jones; Mohammad S Niaz; Cynthia M Brooks; Shannon I Roberson; Maria P Aguinaga; Edward R Hills; Valerie Montgomery Rice; Phillip Bourne; Donald Bruce; Anthony E Archibong Journal: Int J Environ Res Public Health Date: 2009-03-16 Impact factor: 3.390