| Literature DB >> 9692 |
T Shimazu, H Matsushita, K Ishikawa.
Abstract
Cholinergic stimulation of the lateral hypothalamic neurons with intrahypothalamic microinjections of acetylcholine or carbachol caused a marked increase in the content of the active form of glycogen (starch) synthase in the liver. Total activity of the enzyme (active plus inactive forms) was not increased significantly. The lowest effective dose of acetylcholine was 5 X 10(-10) mole, and the optimum dose was 5 X 10(-9) mole. Similar applications of other neurotransmitters, such as norepinephrine, dopamine, serotonin, and gamma-aminobutyric acid, did not affect the enzyme's activity.Entities:
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Year: 1976 PMID： 9692 DOI： 10.1126/science.9692
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728