Literature DB >> 9690613

Evaluation of a rough mutant of Brucella melitensis in pregnant goats.

P H Elzer1, F M Enright, J R McQuiston, S M Boyle, G G Schurig.   

Abstract

Brucella melitensis strain VTRM1, a rough derivative of B melitensis strain 16M, is able to colonise the lymph nodes of goats, does not induce abortion in pregnant goats when used at doses leading to abortions with virulent strain 16M, and does not induce anti-O chain antibodies. However, strain VTRM1 as a single dose vaccine induces only partial protection against both infection and abortion following challenge.

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Year:  1998        PMID： 9690613     DOI： 10.1016/s0034-5288(98)90135-7

Source DB:  PubMed          Journal:  Res Vet Sci        ISSN： 0034-5288            Impact factor:   2.534


  11 in total

1.  In vivo differences in the virulence, pathogenicity, and induced protective immunity of wboA mutants from genetically different parent Brucella spp.

Authors:  Zhen Wang; Jianrui Niu; Shuangshan Wang; Yanli Lv; Qingmin Wu
Journal:  Clin Vaccine Immunol       Date:  2012-12-12

2.  Comparison of protective efficacy of subcutaneous versus intranasal immunization of mice with a Brucella melitensis lipopolysaccharide subunit vaccine.

Authors:  Apurba K Bhattacharjee; Mina J Izadjoo; Wendell D Zollinger; Mikeljon P Nikolich; David L Hoover
Journal:  Infect Immun       Date:  2006-10       Impact factor: 3.441

3.  Protective properties of rifampin-resistant rough mutants of Brucella melitensis.

Authors:  R Adone; F Ciuchini; C Marianelli; M Tarantino; C Pistoia; G Marcon; P Petrucci; M Francia; G Riccardi; P Pasquali
Journal:  Infect Immun       Date:  2005-07       Impact factor: 3.441

4.  Recombinant Ochrobactrum anthropi expressing Brucella abortus Cu,Zn superoxide dismutase protects mice against B. abortus infection only after switching of immune responses to Th1 type.

Authors:  Yongqun He; Ramesh Vemulapalli; Gerhardt G Schurig
Journal:  Infect Immun       Date:  2002-05       Impact factor: 3.441

Review 5.  Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host.

Authors:  R Martin Roop; Jennifer M Gaines; Eric S Anderson; Clayton C Caswell; Daniel W Martin
Journal:  Med Microbiol Immunol       Date:  2009-09-22       Impact factor: 3.402

6.  Human Brucellosis and Adverse Pregnancy Outcomes.

Authors:  Angela M Arenas-Gamboa; Carlos A Rossetti; Sankar P Chaki; Daniel G Garcia-Gonzalez; Leslie G Adams; Thomas A Ficht
Journal:  Curr Trop Med Rep       Date:  2016-10-01

Review 7.  The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine Tuberculosis.

Authors:  Aseem Pandey; Ana Cabello; Lavoisier Akoolo; Allison Rice-Ficht; Angela Arenas-Gamboa; David McMurray; Thomas A Ficht; Paul de Figueiredo
Journal:  PLoS Negl Trop Dis       Date:  2016-08-18

8.  Novel Solutions for Vaccines and Diagnostics To Combat Brucellosis.

Authors:  Satadru Sekhar Mandal; Lucy Duncombe; N Vijaya Ganesh; Susmita Sarkar; Laurence Howells; Philip J Hogarth; David R Bundle; John McGiven
Journal:  ACS Cent Sci       Date:  2017-03-03       Impact factor: 14.553

Review 9.  Uncovering the Hidden Credentials of Brucella Virulence.

Authors:  R Martin Roop; Ian S Barton; Dariel Hopersberger; Daniel W Martin
Journal:  Microbiol Mol Biol Rev       Date:  2021-02-10       Impact factor: 11.056

10.  Evaluation of shedding, tissue burdens, and humoral immune response in goats after experimental challenge with the virulent Brucella melitensis strain 16M and the reduced virulence vaccine strain Rev. 1.

Authors:  Jennifer L Higgins; Mercedes Gonzalez-Juarrero; Richard A Bowen
Journal:  PLoS One       Date:  2017-10-13       Impact factor: 3.240
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