Literature DB >> 9675766

Some reactions of 2-cyanomethylimidazo[4,5-b]pyridine with isothiocyanates. Antituberculotic activity of the obtained compounds.

L Bukowski1, M Janowiec, Z Zwolska-Kwiek, Z Andrzejczyk.   

Abstract

Some reactions of 2-cyanomethylimidazo[4,5-b]pyridine with isothiocyanates were carried out. New derivatives of imidazo[4,5-b]pyridine with different substituents in 2-position and derivatives of the new thiazolo-pyrido-imidazo-pyrimidine ring system were synthesized. Most of the obtained compounds were tested in vitro for their antituberculotic activity.

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Year:  1998        PMID: 9675766

Source DB:  PubMed          Journal:  Pharmazie        ISSN: 0031-7144            Impact factor:   1.267


  3 in total

1.  Microwave-assisted synthesis of a novel class of imidazolylthiazolidin-4-ones and evaluation of its biological activities.

Authors:  Sachin G Modha; Vaibhav P Mehta; Denis Ermolat'ev; Jan Balzarini; Kristof Van Hecke; Luc Van Meervelt; Erik Van der Eycken
Journal:  Mol Divers       Date:  2010-01-19       Impact factor: 3.364

2.  Optimized Synthesis of New Thiosemicarbazide Derivatives with Tuberculostatic Activity.

Authors:  Corina Popovici; Cristina-Maria Pavel; Valeriu Sunel; Corina Cheptea; Dan Gheorghe Dimitriu; Dana Ortansa Dorohoi; Diana David; Valentina Closca; Marcel Popa
Journal:  Int J Mol Sci       Date:  2021-11-09       Impact factor: 5.923

3.  Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.

Authors:  Ravindra K Rawal; S B Katti; Neerja Kaushik-Basu; Payal Arora; Zhenhua Pan
Journal:  Bioorg Med Chem Lett       Date:  2008-10-08       Impact factor: 2.823

  3 in total

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