| Literature DB >> 9672705 |
L K Jeong1, Y A Lee, H R Moon, M W Chun.
Abstract
Novel apio dideoxynucleosides with azido or amino or amino substituent were synthesized starting from 1,3-dihydroxyacetone utilizing an acid-catalyzed 1,4-conjugated addition as a key step and evaluated for antiviral activity. Unfortunately, they were found to be neither active against HIV-1, HSV-1,2 and poliovirus nor toxic.Entities:
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Year: 1998 PMID： 9672705 DOI： 10.1080/07328319808003481
Source DB: PubMed Journal: Nucleosides Nucleotides ISSN： 0732-8311