| Literature DB >> 9666323 |
R Giegé1, M Frugier, J Rudinger.
Abstract
Mimics recapitulating the structural features of tRNAs are involved in biological processes other than ribosome-dependent protein synthesis. A knowledge of the rules underlying the architecture and function of tRNAs allows the design of non-natural mimics. The study of these mimics sheds light upon links between replication, translation and metabolic pathways, leads to biotechnological applications, and provides experimental and conceptual tools for the exploration of primordial evolutionary processes.Mesh：
Substances：
Year: 1998 PMID： 9666323 DOI： 10.1016/s0959-440x(98)80060-2
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809