Literature DB >> 9650725

Hypolipidemic effect of flavonoids from Solanum melongena.

S Sudheesh1, G Presannakumar, S Vijayakumar, N R Vijayalakshmi.   

Abstract

Flavonoids extracted from the fruits of Solanum melongena (Brinjal) orally administered at a dose of 1 mg/100 g BW/day showed significant hypolipidemic action in normal and cholesterol fed rats. HMG CoA reductase activity was found to be enhanced, while activities of glucose-6-phosphate dehydrogenase and malate dehydrogenase were significantly reduced. Activities of lipoprotein lipase and plasma LCAT showed significant enhancement. A significant increase in the concentrations of hepatic and fecal bile acids and fecal neutral sterols was also observed indicating a higher rate of degradation of cholesterol.

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Year:  1997        PMID： 9650725     DOI： 10.1023/a:1007965927434

Source DB:  PubMed          Journal:  Plant Foods Hum Nutr        ISSN： 0921-9668            Impact factor:   3.921


  9 in total

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  9 in total
  9 in total

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  9 in total

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