BACKGROUND: Daytime sleepiness and fatigue is a frequent complaint of obese patients even among those who do not demonstrate sleep apnea. OBJECTIVE: To assess in the sleep laboratory whether obese patients without sleep apnea are sleepier during the day compared with healthy controls with normal weight. METHODS: Our sample consisted of 73 obese patients without sleep apnea, upper airway resistance syndrome, or hypoventilation syndrome who were consecutively referred for treatment of their obesity and 45 controls matched for age. All patients and healthy controls were monitored in the sleep laboratory for 8 hours at night and at 2 daytime naps, each for 1 hour the following day. RESULTS: Obese patients compared with controls were sleepier during the day and their nighttime sleep was disturbed. During both naps, sleep latency, wake time after onset of sleep, and total wake time were significantly lower, whereas the percentage of sleep time was significantly higher in obese patients compared with controls. In contrast, during the nighttime testing, obese patients compared with controls demonstrated significantly higher wake time after onset of sleep, total wake time, and lower percentage of sleep time. An analysis of the relation between nighttime and daytime sleep suggested that daytime sleepiness in obese patients is a result of a circadian abnormality rather than just being secondary to nighttime sleep disturbance. CONCLUSIONS: Daytime sleepiness is a morbid characteristic of obese patients with a potentially significant impact on their lives and public safety. Daytime sleepiness in individuals with obesity appears to be related to a metabolic and/or circadian abnormality of the disorder.
BACKGROUND: Daytime sleepiness and fatigue is a frequent complaint of obesepatients even among those who do not demonstrate sleep apnea. OBJECTIVE: To assess in the sleep laboratory whether obesepatients without sleep apnea are sleepier during the day compared with healthy controls with normal weight. METHODS: Our sample consisted of 73 obesepatients without sleep apnea, upper airway resistance syndrome, or hypoventilation syndrome who were consecutively referred for treatment of their obesity and 45 controls matched for age. All patients and healthy controls were monitored in the sleep laboratory for 8 hours at night and at 2 daytime naps, each for 1 hour the following day. RESULTS:Obesepatients compared with controls were sleepier during the day and their nighttime sleep was disturbed. During both naps, sleep latency, wake time after onset of sleep, and total wake time were significantly lower, whereas the percentage of sleep time was significantly higher in obesepatients compared with controls. In contrast, during the nighttime testing, obesepatients compared with controls demonstrated significantly higher wake time after onset of sleep, total wake time, and lower percentage of sleep time. An analysis of the relation between nighttime and daytime sleep suggested that daytime sleepiness in obesepatients is a result of a circadian abnormality rather than just being secondary to nighttime sleep disturbance. CONCLUSIONS:Daytime sleepiness is a morbid characteristic of obesepatients with a potentially significant impact on their lives and public safety. Daytime sleepiness in individuals with obesity appears to be related to a metabolic and/or circadian abnormality of the disorder.
Authors: Elizabeth Adler; Anand Dhruva; Patricia J Moran; Jennifer Daubenmier; Michael Acree; Elissa S Epel; Peter Bacchetti; Aric A Prather; Ashley Mason; Frederick M Hecht Journal: J Altern Complement Med Date: 2016-12-28 Impact factor: 2.579
Authors: Amanda M Rach; Valerie McLaughlin Crabtree; Tara M Brinkman; Lonnie Zeltzer; Jordan Gilleland Marchak; Deokumar Srivastava; Brooklee Tynes; Jin-Shei Lai; Leslie L Robison; Gregory T Armstrong; Kevin R Krull Journal: J Cancer Surviv Date: 2016-11-12 Impact factor: 4.442
Authors: Susan Dickerson Mayes; Susan L Calhoun; Edward O Bixler; Alexandros N Vgontzas; Fauzia Mahr; Jolene Hillwig-Garcia; Belal Elamir; Linda Edhere-Ekezie; Matthew Parvin Journal: J Pediatr Psychol Date: 2008-08-01