Literature DB >> 964471

Transit time changes with age in the gastrointestinal tract of the rat.

F Varga.   

Abstract

Using 85Sr-labelled microspheres as nonabsorbable markers, the effect of age on gastrointestinal propulsion motility was determined in conscious rats. There was no significant correlation between the gastric emptying rate or the propulsion motility of the small intestine and the age of the rats. However, the transit time of the intestinal content in the caecum in adult (17- to 20-month-old) rats was about fivefold the value found in weanling (19-day-old) rats. Also the transit time of the large intestine was found to be prolonged by about 70% during the life span investigated.

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Year:  1976        PMID： 964471     DOI： 10.1159/000197947

Source DB:  PubMed          Journal:  Digestion        ISSN： 0012-2823            Impact factor:   3.216


  8 in total

1.  Neuroaxonal dystrophy in aging human sympathetic ganglia.

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2.  Prediction of Oral Drug Absorption in Rats from In Vitro Data.

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Journal:  Pharm Res       Date:  2022-02-15       Impact factor: 4.200

3.  Molecular and functional studies of electrogenic Na(+) transport in the distal colon and rectum of young and elderly subjects.

Authors:  E R Greig; T Mathialahan; R P Boot-Handford; G I Sandle
Journal:  Gut       Date:  2003-11       Impact factor: 23.059

4.  Effects of age, ambient temperature, and heat-stable Escherichia coli enterotoxin on intestinal transit in infant mice.

Authors:  H W Moon; P Y Fung; R E Isaacson; G D Booth
Journal:  Infect Immun       Date:  1979-07       Impact factor: 3.441

5.  Effect of age on gastric emptying of liquid--solid meals in man.

Authors:  J G Moore; C Tweedy; P E Christian; F L Datz
Journal:  Dig Dis Sci       Date:  1983-04       Impact factor: 3.199

6.  Gastric Emptying and Gastrointestinal Transit Compared among Native and Hydrolyzed Whey and Casein Milk Proteins in an Aged Rat Model.

Authors:  Julie E Dalziel; Wayne Young; Catherine M McKenzie; Neill W Haggarty; Nicole C Roy
Journal:  Nutrients       Date:  2017-12-13       Impact factor: 5.717

7.  Rat Intestinal Acetic Acid and Butyric acid and Effects of Age, Sex, and High-fat Diet on the Intestinal Levels in Rats.

Authors:  Soo In Choi; Nayoung Kim; Sun Min Lee; Ryoung Hee Nam; So Ra Kang; Chin-Hee Song; Young-Tae Park; Huitae Min; Yeon-Ran Kim; Yeong-Jae Seok
Journal:  J Cancer Prev       Date:  2019-03-30

8.  The bacterial density of clinical rectal swabs is highly variable, correlates with sequencing contamination, and predicts patient risk of extraintestinal infection.

Authors:  Rishi Chanderraj; Christopher A Brown; Kevin Hinkle; Nicole Falkowski; Robert J Woods; Robert P Dickson
Journal:  Microbiome       Date:  2022-01-06       Impact factor: 14.650
  8 in total

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