OBJECTIVES: To show the reducing effect of estrogens and progestins on the elevated intraocular pressure (IOP) in the case of a 56-year-old woman showing typical climacteric complaints, who was admitted to the menopause outpatient unit. She also suffered from a primary open-angle glaucoma treated with betaophtiole eye drops with intraocular pressures of 16-20 mmHg under this local therapy. METHODS: IOP patterns were monitored by means of standardised daily pressure profiles four times a day before as well as 4 and 12 weeks after the beginning of hormone replacement therapy (HRT). The local glaucoma therapy remained unchanged. RESULTS: During HRT, IOP levels were reduced from 16-20 mmHg before therapy to 12-15 mmHg at week 4 and to 13-15 mmHg at week 12 after the beginning of HRT. CONCLUSION: The finding of a close chronological relationship between the onset of menopause and the development of a glaucoma is a potentially new indication for HRT.
OBJECTIVES: To show the reducing effect of estrogens and progestins on the elevated intraocular pressure (IOP) in the case of a 56-year-old woman showing typical climacteric complaints, who was admitted to the menopause outpatient unit. She also suffered from a primary open-angle glaucoma treated with betaophtiole eye drops with intraocular pressures of 16-20 mmHg under this local therapy. METHODS: IOP patterns were monitored by means of standardised daily pressure profiles four times a day before as well as 4 and 12 weeks after the beginning of hormone replacement therapy (HRT). The local glaucoma therapy remained unchanged. RESULTS: During HRT, IOP levels were reduced from 16-20 mmHg before therapy to 12-15 mmHg at week 4 and to 13-15 mmHg at week 12 after the beginning of HRT. CONCLUSION: The finding of a close chronological relationship between the onset of menopause and the development of a glaucoma is a potentially new indication for HRT.
Authors: Thasarat S Vajaranant; Pauline M Maki; Louis R Pasquale; Anne Lee; Hajwa Kim; Mary N Haan Journal: Am J Ophthalmol Date: 2016-03-03 Impact factor: 5.258
Authors: Thasarat S Vajaranant; Brandon R Grossardt; Pauline M Maki; Louis R Pasquale; Arthur J Sit; Lynne T Shuster; Walter A Rocca Journal: Menopause Date: 2014-04 Impact factor: 2.953
Authors: Thasarat Sutabutr Vajaranant; Roberta M Ray; Louis R Pasquale; Julie A Mares; Robert Ritch; Emily W Gower; Mary N Haan; Rebecca D Jackson; Pauline M Maki Journal: Am J Ophthalmol Date: 2018-08-04 Impact factor: 5.258