AIM: To determine the prevalence of diabetic retinopathy in patients with Down's syndrome and diabetes mellitus. METHODS: Nine patients with Down's syndrome and diabetes mellitus were assessed. Factors recorded included type and duration of diabetes, level of diabetic control, blood pressure, urinalysis, and results of ophthalmological examination. RESULTS: The duration of diabetes ranged from 8 to 41 years (mean 17.6 years). All had satisfactory glycaemic control and blood pressure measurements on the low side of normal (mean 106.6/70 mm Hg). One patient had early background diabetic retinopathy. The remainder had no evidence of diabetic retinopathy. CONCLUSION: The low prevalence of diabetic retinopathy in these Down's syndrome patients, despite the long duration, is an interesting finding. It suggests some inherent protective factor against the development of diabetic retinopathy in this patient subgroup.
AIM: To determine the prevalence of diabetic retinopathy in patients with Down's syndrome and diabetes mellitus. METHODS: Nine patients with Down's syndrome and diabetes mellitus were assessed. Factors recorded included type and duration of diabetes, level of diabetic control, blood pressure, urinalysis, and results of ophthalmological examination. RESULTS: The duration of diabetes ranged from 8 to 41 years (mean 17.6 years). All had satisfactory glycaemic control and blood pressure measurements on the low side of normal (mean 106.6/70 mm Hg). One patient had early background diabetic retinopathy. The remainder had no evidence of diabetic retinopathy. CONCLUSION: The low prevalence of diabetic retinopathy in these Down's syndrome patients, despite the long duration, is an interesting finding. It suggests some inherent protective factor against the development of diabetic retinopathy in this patient subgroup.
Authors: J M Lewis; L Jovanovic-Peterson; I Ahmadizadeh; W Bevier; C M Peterson; B Williams Journal: J Diabetes Complications Date: 1994 Jan-Mar Impact factor: 2.852
Authors: M Cignarelli; M L De Cicco; A Damato; A Paternostro; S Pagliarini; S Santoro; L Cardia; G De Pergola; R Giorgino Journal: Diabetes Care Date: 1992-08 Impact factor: 19.112
Authors: Nansi S Boghossian; Nellie I Hansen; Edward F Bell; Barbara J Stoll; Jeffrey C Murray; Abbot R Laptook; Seetha Shankaran; Michele C Walsh; Abhik Das; Rosemary D Higgins Journal: Pediatrics Date: 2010-11-22 Impact factor: 7.124
Authors: Kwan-Hyuck Baek; Alexander Zaslavsky; Ryan C Lynch; Carmella Britt; Yoshiaki Okada; Richard J Siarey; M William Lensch; In-Hyun Park; Sam S Yoon; Takashi Minami; Julie R Korenberg; Judah Folkman; George Q Daley; William C Aird; Zygmunt Galdzicki; Sandra Ryeom Journal: Nature Date: 2009-05-20 Impact factor: 49.962