Literature DB >> 9635854

Encephalopathy, lactic acidosis, hyperammonaemia and 5-fluorouracil toxicity.

D Valik.   

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Year:  1998        PMID: 9635854      PMCID: PMC2150046          DOI: 10.1038/bjc.1998.282

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


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  11 in total

1.  Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.

Authors:  X Wei; H L McLeod; J McMurrough; F J Gonzalez; P Fernandez-Salguero
Journal:  J Clin Invest       Date:  1996-08-01       Impact factor: 14.808

Review 2.  Renal and hepatic nitrogen metabolism in systemic acid base regulation.

Authors:  W G Guder; D Häussinger; W Gerok
Journal:  J Clin Chem Clin Biochem       Date:  1987-08

3.  Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.

Authors:  W Lewis; E S Levine; B Griniuviene; K O Tankersley; J M Colacino; J P Sommadossi; K A Watanabe; F W Perrino
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

Review 4.  Hepatic purine and pyrimidine metabolism: implications for antiviral chemotherapy of viral hepatitis.

Authors:  T Shaw; S A Locarnini
Journal:  Liver       Date:  1995-08

5.  High-dose 5-fluorouracil infusional therapy is associated with hyperammonaemia, lactic acidosis and encephalopathy.

Authors:  K H Yeh; A L Cheng
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

6.  The arterial blood ketone body ratio as a possible marker of multi-organ failure in patients with alcoholic hepatitis.

Authors:  T Saibara; T Maeda; S Onishi; Y Yamamoto
Journal:  Liver       Date:  1994-04

7.  The clinical significance of the arterial ketone body ratio as an early indicator of graft viability in human liver transplantation.

Authors:  K Asonuma; S Takaya; R Selby; R Okamoto; Y Yamamoto; T Yokoyama; S Todo; K Ozawa; T E Starzl
Journal:  Transplantation       Date:  1991-01       Impact factor: 4.939

8.  Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea.

Authors:  R Meinsma; P Fernandez-Salguero; A B Van Kuilenburg; A H Van Gennip; F J Gonzalez
Journal:  DNA Cell Biol       Date:  1995-01       Impact factor: 3.311

9.  Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism.

Authors:  C Szumlanski; D Otterness; C Her; D Lee; B Brandriff; D Kelsell; N Spurr; L Lennard; E Wieben; R Weinshilboum
Journal:  DNA Cell Biol       Date:  1996-01       Impact factor: 3.311

10.  AZT causes tissue-specific inhibition of mitochondrial bioenergetic function.

Authors:  J S Modica-Napolitano
Journal:  Biochem Biophys Res Commun       Date:  1993-07-15       Impact factor: 3.575

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