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Literature DB >> 9020500

High-dose 5-fluorouracil infusional therapy is associated with hyperammonaemia, lactic acidosis and encephalopathy.

K H Yeh, A L Cheng.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 1997 PMID： 9020500 PMCID： PMC2063385 DOI： 10.1038/bjc.1997.79

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

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18 in total

1. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. A potentially more common pharmacogenetic syndrome.

Authors: B E Harris; J T Carpenter; R B Diasio
Journal: Cancer Date: 1991-08-01 Impact factor: 6.860

2. Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity.

Authors: M Tuchman; J S Stoeckeler; D T Kiang; R F O'Dea; M L Ramnaraine; B L Mirkin
Journal: N Engl J Med Date: 1985-07-25 Impact factor: 91.245

3. Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.

Authors: R B Diasio; T L Beavers; J T Carpenter
Journal: J Clin Invest Date: 1988-01 Impact factor: 14.808

4. The thiamine status of patients with cancer as determined by the red cell transketolase activity.

Authors: T K Basu; J W Dickerson; R W Raven; D C Williams
Journal: Int J Vitam Nutr Res Date: 1974 Impact factor: 1.784

5. Biochemical basis for fluorouracil neurotoxicity. The role of Krebs cycle inhibition by fluoroacetate.

Authors: H Koenig; A Patel
Journal: Arch Neurol Date: 1970-08

6. Severe 5-fluorouracil toxicity in a patient with decreased dihydropyrimidine dehydrogenase activity.

Authors: A P Lyss; R C Lilenbaum; B E Harris; R B Diasio
Journal: Cancer Invest Date: 1993 Impact factor: 2.176

7. Thiamin status of patients treated with drug combinations containing 5-fluorouracil.

Authors: M Aksoy; T K Basu; J Brient; J W Dickerson
Journal: Eur J Cancer Date: 1980-08 Impact factor: 9.162

8. A phase II study of weekly 24-hour infusion with high-dose fluorouracil with leucovorin in colorectal carcinoma.

Authors: B Ardalan; L Chua; E M Tian; R Reddy; K Sridhar; P Benedetto; S Richman; A Legaspi; S Waldman; L Morrell
Journal: J Clin Oncol Date: 1991-04 Impact factor: 44.544

9. Dihydropyrimidine dehydrogenase activity in cancer patients.

Authors: R A Fleming; G A Milano; M H Gaspard; P J Bargnoux; A Thyss; R Plagne; N Renée; M Schneider; F Demard
Journal: Eur J Cancer Date: 1993 Impact factor: 9.162

10. Clearance of continuously infused 5-fluorouracil in adults having lung or gastrointestinal carcinoma with or without hepatic metastases.

Authors: R A Floyd; C L Hornbeck; J E Byfield; J C Griffiths; S S Frankel
Journal: Drug Intell Clin Pharm Date: 1982-09

29 in total

1. AMP-activated protein kinase signaling regulated expression of urea cycle enzymes in response to changes in dietary protein intake.

Authors: Sandra K Heibel; Peter J McGuire; Nantaporn Haskins; Himani D Majumdar; Sree Rayavarapu; Kanneboyina Nagaraju; Yetrib Hathout; Kristy Brown; Mendel Tuchman; Ljubica Caldovic
Journal: J Inherit Metab Dis Date: 2019-08-01 Impact factor: 4.982

2. A case of 5-fluorouracil induced encephalopathy.

Authors: Kyung A Kwon; Hyuk-Chan Kwon; Min Chan Kim; Sung-Hyun Kim; Sung Yong Oh; Suee Lee; Hyo-Jin Kim
Journal: Cancer Res Treat Date: 2010-06-30 Impact factor: 4.679

3. 5-FU-induced leukoencephalopathy with reversible lesion of splenium of corpus callosum in a patient with colorectal cancer.

Authors: Gyanendra Acharya; Maria T Cruz Carreras; Terry Wynne Rice
Journal: BMJ Case Rep Date: 2017-11-21

4. Noncirrhotic hyperammonemia causing relapsing altered mental status.

Authors: Chibuzo Clement Odigwe; Binod Khatiwada; Christopher Holbrook; Ifeoma Sylvia Ekeh; Chukwuemeka Uzoka; Isaac Ikwu; Bishwas Upadhyay
Journal: Proc (Bayl Univ Med Cent) Date: 2015-10

5. Hyperammonemic encephalopathy associated with 5-fluorouracil in a patient with previous orthotopic liver transplantation.

Authors: Hemnishil K Marella; Rahul Peravali; Amit L Jain; Satheesh Nair; Benedict Maliakkal; Uchenna Agbim; Rajanshu Verma
Journal: Proc (Bayl Univ Med Cent) Date: 2020-01-09