Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Computer simulation of movement-generating cross-bridges.

Literature DB >> 963202

Computer simulation of movement-generating cross-bridges.

Abstract

A stochastic computational method was developed to study properties of cross-bridge models for muscle contraction, by following the time history of individual cross-bridge model of Andrew Huxley (1957) and a modified two-state model with more realistic behavior during steady stretching are used as examples. The method can readily compute steady-state force during shortening and stretching and force-transients following rapid changes in length. Computations of velocity with a steady load and of velocity transients are more sensitive to the randomness inherent in the stochastic method.

Entities: Disease

Mesh：

Year: 1976 PMID： 963202 PMCID： PMC1334942 DOI： 10.1016/S0006-3495(76)85752-9

Source DB: PubMed Journal: Biophys J ISSN： 0006-3495 Impact factor: 4.033

12 in total

7. On the theory of ion transport across the nerve membrane, VII. Cooperativity between channels of a large square lattice.

Authors: Y D Chen; T L Hill
Journal: Proc Natl Acad Sci U S A Date: 1973-01 Impact factor: 11.205

8. A model for the transient and steady-state mechanical behavior of contracting muscle.

Authors: F J Julian; K R Sollins; M R Sollins
Journal: Biophys J Date: 1974-07 Impact factor: 4.033

9. Proposed mechanism of force generation in striated muscle.

Authors: A F Huxley; R M Simmons
Journal: Nature Date: 1971-10-22 Impact factor: 49.962

10. Computer simulation of flagellar movement. I. Demonstration of stable bend propagation and bend initiation by the sliding filament model.

Authors: C J Brokaw
Journal: Biophys J Date: 1972-05 Impact factor: 4.033

17 in total

1. A weakly coupled version of the Huxley crossbridge model can simulate energetics of amphibian and mammalian skeletal muscle.

Authors: C J Barclay
Journal: J Muscle Res Cell Motil Date: 1999-02 Impact factor: 2.698

5. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations.

Authors: Yi-der Chen; Bo Yan; Robert J Rubin
Journal: Biophys J Date: 2002-11 Impact factor: 4.033

10. Direct tests of muscle cross-bridge theories: predictions of a Brownian dumbbell model for position-dependent cross-bridge lifetimes and step sizes with an optically trapped actin filament.

Authors: D A Smith
Journal: Biophys J Date: 1998-12 Impact factor: 4.033

Computer simulation of movement-generating cross-bridges.

Review 1. Muscle filament structure and muscle contraction.

2. Very high tension with very little ATP breakdown by active skeletal muscle.

3. Some self-consistent two-state sliding filament models of muscle contraction.

4. Muscle structure and theories of contraction.

5. Molecular mechanism for oscillation in flagella and muscle.

Review 6. Theoretical formalism for the sliding filament model of contraction of striated muscle. Part I.

7. On the theory of ion transport across the nerve membrane, VII. Cooperativity between channels of a large square lattice.

8. A model for the transient and steady-state mechanical behavior of contracting muscle.

9. Proposed mechanism of force generation in striated muscle.

10. Computer simulation of flagellar movement. I. Demonstration of stable bend propagation and bend initiation by the sliding filament model.

1. A weakly coupled version of the Huxley crossbridge model can simulate energetics of amphibian and mammalian skeletal muscle.

2. Protein-protein ratchets: stochastic simulation and application to processive enzymes.

3. Thermodynamic features of myosin filament suspensions: implications for the modeling of muscle contraction.

4. Orientational changes of crossbridges during single turnover of ATP.

5. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations.

6. Dynamics of single-motor molecules: the thermal ratchet model.

7. Bend propagation in flagella. II. Incorporation of dynein cross-bridge kinetics into the equations of motion.

8. Simulation of stochastic processes in motile crossbridge systems.

9. Computer simulation of flagellar movement. IV. Properties of an oscillatory two-state cross-bridge model.

10. Direct tests of muscle cross-bridge theories: predictions of a Brownian dumbbell model for position-dependent cross-bridge lifetimes and step sizes with an optically trapped actin filament.