Literature DB >> 9622650

Gender-specific apposition between vasoactive intestinal peptide-containing axons and gonadotrophin-releasing hormone-producing neurons in the rat.

T L Horvath1, V Cela, E M van der Beek.   

Abstract

Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by VIP axons were higher in females than in males. This sexual dimorphic interaction of VIP fibers and GnRH neurons may indicate the involvement of VIP in the gender-specific regulation of gonadotrophin release in rats. Copyright 1998 Elsevier Science B.V. All rights reserved.

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Year:  1998        PMID： 9622650     DOI： 10.1016/s0006-8993(98)00208-x

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  25 in total

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