| Literature DB >> 23550016 |
Abstract
Female reproductive functioning requires the precise temporal -organization of numerous neuroendocrine events by a master circadian brain clock located in the suprachiasmatic nucleus. Across species, including humans, disruptions to circadian timing result in pronounced deficits in ovulation and fecundity. The present chapter provides an overview of the circadian control of female reproduction, underscoring the significance of kisspeptin as a key locus of integration for circadian and steroidal signaling necessary for the initiation of ovulation.Entities:
Mesh:
Substances:
Year: 2013 PMID: 23550016 PMCID: PMC4385794 DOI: 10.1007/978-1-4614-6199-9_18
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622