Literature DB >> 9614893

[Late intestinal complications of adjuvant radiotherapy of rectal cancers].

J F Bosset1, N Meneveau, J J Pavy.   

Abstract

Pre or postoperative pelvic irradiation has demonstrated a definitive efficacy in reducing the local failure rate of rectal cancer treated with surgery alone. However it can induce late small bowel morbidity that could alter the therapeutic ratio. The clinical pictures of radiation enteritis include obstruction and diarrhea/malabsorption. Prognostic factors that increase the risk of late small bowel complications include extended fields out of the pelvis, irradiation dose, inappropriate irradiation technique, and increased small bowel irradiated volumes. The addition of chemotherapy increases acute but not late toxicity. Recommendations concerning the clinical practice are described. Radiotherapy may also alter the residual sphincter function and we recommend to assess correctly these complications.

Entities:  

Mesh:

Year:  1997        PMID: 9614893     DOI: 10.1016/s1278-3218(97)82955-1

Source DB:  PubMed          Journal:  Cancer Radiother        ISSN: 1278-3218            Impact factor:   1.018


  3 in total

1.  Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications.

Authors:  Leire Arbea; Luis Isaac Ramos; Rafael Martínez-Monge; Marta Moreno; Javier Aristu
Journal:  Radiat Oncol       Date:  2010-02-26       Impact factor: 3.481

2.  Prospective study of neoadjuvant chemoradiotherapy using intensity-modulated radiotherapy and 5 fluorouracil for locally advanced rectal cancer - toxicities and response assessment.

Authors:  David K Simson; Swarupa Mitra; Parveen Ahlawat; Upasna Saxena; Manoj Kumar Sharma; Sheh Rawat; Harpreet Singh; Babita Bansal; Lalitha Kameshwari Sripathi; Aditi Tanwar
Journal:  Cancer Manag Res       Date:  2018-03-19       Impact factor: 3.989

3.  A comparison of dosimetric parameters between tomotherapy and three-dimensional conformal radiotherapy in rectal cancer.

Authors:  Mina Yu; Joo Hwan Lee; Hong Seok Jang; Dong Min Jeon; Jae Suk Cheon; Hyo Chun Lee; Jong Hoon Lee
Journal:  Radiat Oncol       Date:  2013-07-16       Impact factor: 3.481

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.