Literature DB >> 9613966

Determination of nicotine, cotinine and caffeine in meconium using high-performance liquid chromatography.

J Baranowski1, G Pochopień, I Baranowska.   

Abstract

A high-performance liquid chromatographic method with diode-array detection for the determination of nicotine and its metabolites, cotinine and caffeine, in meconium is described. This method is suitable to assess foetus exposure to tobacco smoke. The analytes were extracted by solid-phase extraction before chromatography. From among 30 meconium samples 11 were positive for cotinine (20-86 ng/g) and 27 for caffeine (10-45 ng/g). No nicotine was present in the samples because of its rapid metabolism into cotinine.

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Year:  1998        PMID: 9613966     DOI: 10.1016/s0378-4347(97)00619-1

Source DB:  PubMed          Journal:  J Chromatogr B Biomed Sci Appl        ISSN: 1387-2273


  8 in total

1.  Nicotine and metabolites in meconium as evidence of maternal cigarette smoking during pregnancy and predictors of neonatal growth deficits.

Authors:  Teresa R Gray; Rina D Eiden; Kenneth E Leonard; Gerard Connors; Shannon Shisler; Marilyn A Huestis
Journal:  Nicotine Tob Res       Date:  2010-04-28       Impact factor: 4.244

2.  An epidemiologic study comparing fetal exposure to tobacco smoke in three Southeast Asian countries.

Authors:  Enrique M Ostrea; Esterlita Villanueva-Uy; Sopapan Ngerncham; Luephorn Punnakanta; Melissa J P Batilando; Pratibha Agarwal; Elizabeth Pensler; Melissa Corrion; Erwin F Ramos; Joshua Romero; Ronald L Thomas
Journal:  Int J Occup Environ Health       Date:  2008 Oct-Dec

Review 3.  Bioanalytical procedures for monitoring in utero drug exposure.

Authors:  Teresa Gray; Marilyn Huestis
Journal:  Anal Bioanal Chem       Date:  2007-03-17       Impact factor: 4.142

4.  Monitoring of prenatal exposure to organic and inorganic contaminants using meconium from an Eastern Canada cohort.

Authors:  Raphael Cassoulet; Lounes Haroune; Nadia Abdelouahab; Virginie Gillet; Andrea A Baccarelli; Hubert Cabana; Larissa Takser; Jean-Philippe Bellenger
Journal:  Environ Res       Date:  2018-12-19       Impact factor: 6.498

5.  Meconium nicotine and metabolites by liquid chromatography-tandem mass spectrometry: differentiation of passive and nonexposure and correlation with neonatal outcome measures.

Authors:  Teresa R Gray; Raquel Magri; Diaa M Shakleya; Marilyn A Huestis
Journal:  Clin Chem       Date:  2008-10-09       Impact factor: 8.327

6.  Quantification of nicotine, cotinine, trans-3'-hydroxycotinine, nornicotine and norcotinine in human meconium by liquid chromatography/tandem mass spectrometry.

Authors:  Teresa R Gray; Diaa M Shakleya; Marilyn A Huestis
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-01-16       Impact factor: 3.205

7.  Enhanced Chromatographic Determination of Nicotine in Human Plasma: Applied to Human Volunteers.

Authors:  Bassam M Ayoub; Samy Mohamady; Moataz S Hendy; Mohamed M Elmazar
Journal:  Int J Biomed Sci       Date:  2015-12

8.  Caffeine Concentrations in Coffee, Tea, Chocolate, and Energy Drink Flavored E-liquids.

Authors:  Joseph G Lisko; Grace E Lee; J Brett Kimbrell; Michael E Rybak; Liza Valentin-Blasini; Clifford H Watson
Journal:  Nicotine Tob Res       Date:  2017-04-01       Impact factor: 4.244

  8 in total

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