| Literature DB >> 9608902 |
Abstract
Following a brief review of important concepts of vaccine response and vaccine immunology, recent reports on genetic determinants of vaccine response are reviewed. Recent data demonstrating significant associations with particular human leukocyte antigen genes and responsiveness to measles and hepatitis B vaccines are discussed, along with the influence of Km and Gm allotype genes on pneumococcal polysaccharide vaccines. These recent findings have important considerations for research, vaccine development, and clinical practice.Entities:
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Year: 1998 PMID: 9608902 DOI: 10.1097/00008480-199804000-00017
Source DB: PubMed Journal: Curr Opin Pediatr ISSN: 1040-8703 Impact factor: 2.856